N-亚硝基肌氨酸
- 中文名称：
- N-亚硝基肌氨酸
- 中文别名：
- N-亚硝基肌氨酸
- 英文名称：
- Acetic acid,2-(methylnitrosoamino)-
- 英文别名：
- N-nitrososarcosine;
N-Nitrososarcosine;
2-[methyl(nitroso)amino]acetic acid
- CAS No.：
- 13256-22-9
- 分 子 式：
-
C3H6N2O3
- 分 子 量：
- 118.09134
- 精确分子量：
- 118.03800
- PSA：
- 69.97000
- InChI：
- The Key: HJMPSKKJHVWPBK-UHFFFAOYSA-N3
- 安全术语：
| RIDADR | 2811 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
- 分子结构式：
-
- SDS：
- 查看
N-亚硝基肌氨酸 物化性质
- 密度：
- 1.35g/cm3
- 熔点：
- 66-67ºC
- 沸点：
- 353.1ºC at 760mmHg
- 闪点：
- 167.4ºC
- 折射率：
- 1.503
- 蒸汽压：
- 6.18E-06mmHg at 25°C
N-亚硝基肌氨酸 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VQ3150000
- CHEMICAL NAME :
- Sarcosine, N-nitroso-
- CAS REGISTRY NUMBER :
- 13256-22-9
- BEILSTEIN REFERENCE NO. :
- 1756162
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C3-H6-N2-O3
- MOLECULAR WEIGHT :
- 118.11
- WISWESSER LINE NOTATION :
- QV1N1&NO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NATWAY Naturwissenschaften. (Springer-Verlag, Heidelberger Platz 3, D-1000
Berlin 33, Fed. Rep. Ger.) V.1- 1913- Volume(issue)/page/year:
50,100,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 184 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
35,1981,1975
** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 29 gm/kg/41W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 19,1077,1969
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 118 gm/kg/56W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Sense Organs and Special Senses (Ear) - effect, not otherwise specified
Lungs, Thorax, or Respiration - tumors
- REFERENCE :
- FEPRA7 Federation Proceedings, Federation of American Societies for
Experimental Biology. (Bethesda, MD) V.1-46, 1942-87.
Volume(issue)/page/year: 33,596,1974
*** REVIEWS ***
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 17,327,1978
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 17,327,1978
IARC Cancer Review:Group 2B
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,56,1987
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-FRANCE;Carcinogen JAN 1993
