异柳磷,25311-71-1，生产厂家，价格-洛克化工网移动版

异柳磷

中文名称：: 异柳磷

中文别名：: 异柳磷;
异丙胺磷;
O-甲基-0-(邻异丙氧基羰基苯基)硫代磷酰酰胺

英文名称：: ISOFENPHOS

英文别名：: isofenphos;
discus;
isophenphos;
40sd;
le-mat;
Pryfon;
Amaze;
isopropyl (RS)-O-[ethoxy(isopropylamino)phosphinothioyl]salicylate;
O-ethyl O-(2-isopropoxycarbonyl-phenyl-isopropyl) phosphoramidothioate;
OFTANOL;
AMAZE(R);
propan-2-yl 2-{[(Ξ)-P-ethoxy-N-propan-2-ylphosphoramidothioyl]oxy}benzoate;
1-methylethyl 2-[[ethoxy[(1-methylethyl)amino]phosphinothioyl]oxy]benzoate;
[14C]-Isofenphos;
Amidocid;
O-ethyl-O-2-isopropoxycarbonylphenyl-N-isopropyl phosphoroamidothioate;
ISOFENPHOS;
pyrfon;
(RS)-(O-ethyl O-2-isopropoxycarbonylphenyl isopropylphosphoramidothioate)

CAS No.：: 25311-71-1

分子式：: C15H24NO4PS

分子量：: 345.39

精确分子量：: 345.11600

PSA：: 98.69000

MDL：: MFCD00041805

EINECS：: 246-814-1

BRN：: 2949615

InChI：: InChI=1/C15H24NO4PS/c1-6-18-21(22,16-11(2)3)20-14-10-8-7-9-13(14)15(17)19-12(4)5/h7-12H,6H2,1-5H3,(H3

风险术语：: 24/25-50/53

SDS：: 查看

异柳磷制备方法及用途

制备方法

由乙基硫磷酰二氯、水杨酸异丙酯、异丙胺经下列反应而得。将水杨酸异丙酯、乙基硫代磷酰二氯和催化剂投入反应釜，搅拌冷却至10℃左右。缓慢加入一部分氢氧化钠溶液，反应半小时后再将其余的氢氧化钠溶液和异丙胺同时缓慢均匀加入。加毕后再继续反应2h。然后加水和溶剂，搅拌后静置分出下层废水，上层粗油经减压蒸馏即得乙基异柳磷原油。将乙基硫代磷酰二氯用甲基硫代磷酰二氯代替，采用相似工艺可制得甲基异柳磷。原料消耗定额：水杨酸350kg/t、异丙醇580kg/t、硫酸340kg/t、甲醇720kg/t、异丙胺130kg/t、三氯硫磷380kg/t。

合成制备方法

由乙基硫磷酰二氯、水杨酸异丙酯、异丙胺经下列反应而得。将水杨酸异丙酯、乙基硫代磷酰二氯和催化剂投入反应釜，搅拌冷却至10℃左右。缓慢加入一部分氢氧化钠溶液，反应半小时后再将其余的氢氧化钠溶液和异丙胺同时缓慢均匀加入。加毕后再继续反应2h。然后加水和溶剂，搅拌后静置分出下层废水，上层粗油经减压蒸馏即得乙基异柳磷原油。将乙基硫代磷酰二氯用甲基硫代磷酰二氯代替，采用相似工艺可制得甲基异柳磷。原料消耗定额：水杨酸350kg/t、异丙醇580kg/t、硫酸340kg/t、甲醇720kg/t、异丙胺130kg/t、三氯硫磷380kg/t。

用途简介

乙基异柳磷和甲基异柳磷都是良好的防治地下害虫的杀虫剂，可有效地防治金针虫、土蚕、蛴螬、地老虎等多种主要地下害虫；对水稻螟虫、飞虱、叶蝉等也有一定的防效作用。并有兼治线虫的作用

用途

乙基异柳磷和甲基异柳磷都是良好的防治地下害虫的杀虫剂，可有效地防治金针虫、土蚕、蛴螬、地老虎等多种主要地下害虫；对水稻螟虫、飞虱、叶蝉等也有一定的防效作用。并有兼治线虫的作用

异柳磷物化性质

密度：: 1.157g/cm3
熔点：: Less than -12ºC
沸点：: 411.5ºC at 760mmHg
闪点：: 202.7ºC
折射率：: 1.528
蒸汽压：: 5.56E-07mmHg at 25°C
存储条件/存储方法：: 库房通风低温干燥,与食品原料分开储运
其它信息：: 1.       性状：亮黄色油状液体

2.       密度（g/mL,25/4℃）：1.13

3.       相对蒸汽密度（g/mL,空气=1）：未确定

4.       熔点（ºC）：未确定

5.       沸点（ºC,常压）：120

6.       沸点（ºC,5.2kPa）：未确定

7.       折射率：1.5165

8.       闪点（ºC）：未确定

9.       比旋光度（º）：未确定

10.    自燃点或引燃温度（ºC）：未确定

11.    蒸气压（kpa,20ºC）：未确定

12.    饱和蒸气压（kPa,60ºC）：未确定

13.    燃烧热（KJ/mol）：未确定

14.    临界温度（ºC）：未确定

15.    临界压力（KPa）：未确定

16.    油水（辛醇/水）分配系数的对数值：未确定

17.    爆炸上限（%,V/V）：未确定

18.    爆炸下限（%,V/V）：未确定

19.    溶解性：溶于丙酮、醇、醚、苯

异柳磷安全信息

包装等级：: I
风险类别：: 6.1(a)
海关代码：: 2929909012
危险类别码：: 24/25-50/53
安全说明：: S36/37-S45-S60-S61
RTECS号：: VO4395500
危险标志：: T: Toxic;N: Dangerous for the environment;

异柳磷毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VO4395500

CHEMICAL NAME :: Salicylic acid, isopropyl ester, O-ester with O-ethyl isopropylphosphoramidothioate

CAS REGISTRY NUMBER :: 25311-71-1

LAST UPDATED :: 199710

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C15-H24-N-O4-P-S

MOLECULAR WEIGHT :: 345.43

WISWESSER LINE NOTATION :: 1Y1&OVR DOPS&O2&MY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 28 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85ARAE "Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revision Volume(issue)/page/year: 1,118,1977

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 144 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A236,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 188 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) Volume(issue)/page/year: 78-1,39,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 91300 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976 Volume(issue)/page/year: -,-,1971/1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 162 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C173,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 3 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - muscle weakness Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 33,386,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: 13 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 8,551,1984 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2240 mg/kg/8W-I

TOXIC EFFECTS :: Liver - other changes Biochemical - Metabolism (Intermediary) - other proteins

REFERENCE :: IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 21,684,1983 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

毒理学数据：

急性毒性：大鼠口经LD50：28 mg/kg；大鼠吸入LC50：144 mg/m3/4H；小鼠口经LD50：91300 ug/kg

异柳磷海关数据

中国海关编码：2929909012

概述：: 2929909012 异柳磷、甲基异柳磷、丙胺氟磷等退税率:0.0% 监管条件:S(进出口农药登记证明)
申报要素：: 品名, 成分含量, 用途
监管条件：: S.进出口农药登记证明
摘要/Summary：: 2929909012 isopropyl 2-((ethoxy(isopropylamino)phosphorothioyl)oxy)benzoate

异柳磷分子结构与计算化学数据

分子结构数据

1、摩尔折射率：91.89

2、摩尔体积（m³/mol）：298.3

3、等张比容（90.2K）：763.4

4、表面张力（dyne/cm）：42.9

5、极化率（10^-24cm³）：36.42

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:1

3.氢键受体数量:6

4.可旋转化学键数量:9

5.互变异构体数量:2

6.拓扑分子极性表面积88.9

7.重原子数量:22

8.表面电荷:0

9.复杂度:403

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:1

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

异柳磷

异柳磷制备方法及用途