3-甲基-2-苯基吗啉盐酸盐
- 中文名称：
- 3-甲基-2-苯基吗啉盐酸盐
- 中文别名：
- 3-甲基-2-苯基吗啉盐酸盐;
2-苯基-3-甲基四氢-1,4-恶嗪盐酸盐;
3-甲基-2-苯基-,盐酸盐吗啉;
3-甲基-2-苯基-吗啉盐酸盐;
3-甲基-2-苯基四氢-2H-1,4-恶嗪盐酸盐;
芬美曲秦甲基氯化物;
芬美曲秦盐酸盐
- 英文名称：
- Morpholine,3-methyl-2-phenyl-, hydrochloride (1:1)
- 英文别名：
- 3-methyl-2-phenylmorpholine,hydrochloride;
Neo-zine;
Marsin;
Mefolin;
3-Methyl-2-phenylmorpholine hydrochloride;
Probese-P hydrochloride;
USAF GE-1;
Phenmetraline Hydrochloride;
phenmetrazine hydrochloride;
3-Methyl-2-phenyl-morpholin,Hydrochlorid;
A 66 hydrochloride;
Preludin
- CAS No.：
- 1707-14-8
- 分 子 式：
-
C11H15NO.ClH
- 分 子 量：
- 213.73
- 精确分子量：
- 213.09200
- PSA：
- 21.26000
- EINECS：
- 216-950-6
- InChI：
- The Key: VJNXVAVKCZJOFQ-QLSWKGBWSA-N3
- 安全术语：
- Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Human reproductive effects. Human teratogenic effects by ingestion: developmental abnormalities of the respiratory and gastrointestinal systems, and effects on newborn including neonatal measures or effects. When heated to decomposition it emits very toxic fumes of NOx and HCl.
- 分子结构式：
-
- SDS：
- 查看
3-甲基-2-苯基吗啉盐酸盐 物化性质
- 熔点：
- 175-177ºC
- 沸点：
- 285.2ºC at 760mmHg
- 闪点：
- 112.7ºC
- 蒸汽压：
- 0.00284mmHg at 25°C
3-甲基-2-苯基吗啉盐酸盐 安全信息
- 包装等级：
- III
- 风险类别：
- 6.1(b)
- 海关代码：
- 2934999090
3-甲基-2-苯基吗啉盐酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QE6650000
- CHEMICAL NAME :
- Morpholine, 3-methyl-2-phenyl-, hydrochloride
- CAS REGISTRY NUMBER :
- 1707-14-8
- LAST UPDATED :
- 199109
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C11-H15-N-O.Cl-H
- MOLECULAR WEIGHT :
- 213.73
- WISWESSER LINE NOTATION :
- T6M DOTJ B1 CR &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 165 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Gastrointestinal - changes in structure or function of salivary glands
Skin and Appendages - hair
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 13,711,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 175 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
2,589,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
2,589,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 165 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Gastrointestinal - changes in structure or function of salivary glands
Skin and Appendages - hair
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 13,711,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: AD277-689
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 240 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - excitement
Skin and Appendages - hair
- REFERENCE :
- APSXAS Acta Pharmaceutica Suecica. (Apotekarsocieteten-Farmacevtiska
Foereningen, Box 1136, S-111, 81 Stockholm, Sweden) V.1- 1964-
Volume(issue)/page/year: 4,37,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 71 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
2,589,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 41 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,286,1972
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 84 mg/kg
- SEX/DURATION :
- female 28-84 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - respiratory system
Reproductive - Specific Developmental Abnormalities - gastrointestinal
system
Reproductive - Effects on Newborn - other neonatal measures or effects
- REFERENCE :
- BMJOAE British Medical Journal. (British Medical Assoc., BMA House,
Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year:
2,1327,1962
3-甲基-2-苯基吗啉盐酸盐 海关数据
中国海关编码：2934999090
- 概述：
- 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
