海关代码：

32041200

WGK_Germany：

2
德国有关水污染物质的分类清单

危险类别码：

R36

安全说明：

S22-S24/25-S37/39-S26

RTECS号：

LM5900000

安全标志：

S22:不要吸入粉尘。
S24/25:防止皮肤和眼睛接触。

危险标志：

Xi: Irritant;

CHEMICAL IDENTIFICATION

RTECS NUMBER :

LM5900000

CHEMICAL NAME :

Fluorescein, 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-, disodium salt

CAS REGISTRY NUMBER :

18472-87-2

LAST UPDATED :

199701

DATA ITEMS CITED :

11

MOLECULAR FORMULA :

C20-H2-Br4-Cl4-O5.2Na

MOLECULAR WEIGHT :

829.64

WISWESSER LINE NOTATION :

T C666 BO EVJ DE FE IR BG CG DG EG FVO& LE MO NE &-NA- 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

310 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

75600 mg/kg/90W-C

TOXIC EFFECTS :

Tumorigenic - neoplastic by RTECS criteria Liver - tumors Endocrine - tumors

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

63 gm/kg

SEX/DURATION :

female 1-22 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

39600 mg/kg

SEX/DURATION :

female 6-16 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

66 gm/kg

SEX/DURATION :

female 6-16 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

MUTATION DATA

TYPE OF TEST :

Mutation in mammalian somatic cells

TEST SYSTEM :

Human Lung

DOSE/DURATION :

3 mg/L

REFERENCE :

MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 30,239,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4129 No. of Facilities: 301 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 1460 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4129 No. of Facilities: 559 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 9866 (estimated) No. of Female Employees: 3202 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9003 No. of Facilities: 636 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 8722 (estimated) No. of Female Employees: 6754 (estimated)

毒理学数据：

急性毒性：小鼠静脉LC50： 310 mg/kg

计算化学数据

1、   氢键供体数量：0

2、   氢键受体数量：5

3、   可旋转化学键数量：0

4、   拓扑分子极性表面积（TPSA）：81.7

5、   重原子数量：35

6、   表面电荷：0

7、   复杂度：780

8、   同位素原子数量：0

9、   确定原子立构中心数量：0

10、   不确定原子立构中心数量：0

11、   确定化学键立构中心数量：0

12、   不确定化学键立构中心数量：0

13、   共价键单元数量：3

• 
  酸性红92红外图谱(IR1)
• 
  酸性红92红外图谱(IR2)
• 
  酸性红92核磁图(¹HNMR)