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Name:
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(1R,2S)-(-)-Ephedrine hydrochloride, 99.0-101.0% (dry subst.) Material Safety Data Sheet
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Synonym:
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(-)-2-Methylamino-1-phenyl-propane-1-ol hydrochloride; L-alpha-(1-Methylaminoethyl)benzyl alcohol; Benzenemethanol, alpha-[(1S)-1-(methylamino)ethyl]-, hydrochloride, (alphaR); Benzenemethanol, alpha-[1-(methylamino)ethyl]-, hydrochloride, [R-(R,S)]-; Benzenemethanol, alpha-[1-(methylamino)ethyl]-, hydrochloride, [R-(R,)]-; Ephedrine hydrochloride; Ephedrine, hydrochloride, (-)-; L-Ephedrine, hydrochloride; N-Methyl-beta-oxy-beta-phenylisopropylaminhydrochloride
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CAS:
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50-98-6
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Section 1 - Chemical Product
MSDS Name: (1R,2S)-(-)-Ephedrine hydrochloride, 99.0-101.0% (dry subst.) Material Safety Data Sheet
Synonym: (-)-2-Methylamino-1-phenyl-propane-1-ol hydrochloride; L-alpha-(1-Methylaminoethyl)benzyl alcohol; Benzenemethanol, alpha-[(1S)-1-(methylamino)ethyl]-, hydrochloride, (alphaR); Benzenemethanol, alpha-[1-(methylamino)ethyl]-, hydrochloride, [R-(R,S)]-; Benzenemethanol, alpha-[1-(methylamino)ethyl]-, hydrochloride, [R-(R,)]-; Ephedrine hydrochloride; Ephedrine, hydrochloride, (-)-; L-Ephedrine, hydrochloride; N-Methyl-beta-oxy-beta-phenylisopropylaminhydrochloride
SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS
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CAS#
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Chemical Name
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content
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EINECS#
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50-98-6
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(1R,2S)-(-)-Ephedrine hydrochloride
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>99
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200-074-6
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Hazard Symbols: XN
Risk Phrases: 22
SECTION 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW Harmful if swallowed.Light sensitive.The toxicological properties of this material have not been fully investigated. Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. Contact with the skin may cause a local anesthetic effect.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.
SECTION 4 - FIRST AID MEASURES
Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
SECTION 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
SECTION 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Store protected from light.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light.
SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 50-98-6: Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Powder
Color: colorless or white
Odor: None reported.
pH: 5.9 (aq. soln 1:200)
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 217.00 - 220.00 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: freely soluble
Specific Gravity/Density: Not available.
Molecular Formula: C10H15NO.HCl
Molecular Weight: 201.70
SECTION 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. Light sensitive.
Conditions to Avoid:
Incompatible materials, light, dust generation, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents, direct light.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Hazardous Polymerization: Will not occur.
SECTION 11 - TOXICOLOGICAL INFORMATION
RTECS#: CAS# 50-98-6: KB1750000
LD50/LC50:
CAS# 50-98-6: Oral, mouse: LD50 = 400 mg/kg.
Carcinogenicity:
(1R,2S)-(-)-Ephedrine hydrochloride - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
SECTION 12 - ECOLOGICAL INFORMATION
SECTION 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
SECTION 14 - TRANSPORT INFORMATION
IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material.
SECTION 15 - REGULATORY INFORMATION
European/International Regulations European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
Safety Phrases:
S 22 Do not breathe dust. S 25 Avoid contact with eyes. WGK (Water Danger/Protection) CAS# 50-98-6: 1 Canada CAS# 50-98-6 is listed on Canada's DSL List. CAS# 50-98-6 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 50-98-6 is listed on the TSCA inventory.
SECTION 16 - ADDITIONAL INFORMATION
MSDS Creation Date: 9/02/1997 Revision #5 Date: 2/17/2003 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages.
SECTION 16 - ADDITIONAL INFORMATION N/A
