17Β-羟基-3-甲氧基-1,3,5(10)-雌三烯
- 中文名称：
- 17Β-羟基-3-甲氧基-1,3,5(10)-雌三烯
- 中文别名：
- 17-Beta-雌二醇 3-甲醚
- 英文名称：
- Estra-1,3,5(10)-trien-17-ol,3-methoxy-, (17b)-
- 英文别名：
- (8R,9S,13S,14S,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol;
3-methoxyestra-1,3,5(10)-trien-17-|A-ol;
EINECS 213-858-8;
17beta-Estradiol 3-methyl ether;
[3H]-3-Methoxyestradiol;
Oestradiol 3-methyl ether;
[14C]-3-Methoxyestradiol;
3-Methoxyoestradiol;
3-O-Methyl Estradiol;
Estradiol 3-methyl ether;
3-Methoxyestradiol;
Estradiol-17beta-3-methyl ether
- CAS No.：
- 1035-77-4
- 分 子 式：
-
C19H26O2
- 分 子 量：
- 286.45
- 精确分子量：
- 286.19300
- PSA：
- 29.46000
- InChI：
- The Key: ULAADVBNYHGIBP-GFEQUFNTSA-N3
- 风险术语：
- 20/21/22-36-11
- 安全术语：
- Experimental reproductive effects. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes.
- 分子结构式：
-
- SDS：
- 查看
17Β-羟基-3-甲氧基-1,3,5(10)-雌三烯 物化性质
- 密度：
- 1.109 g/cm3
- 沸点：
- 428.8ºC at 760 mmHg
- 闪点：
- 187.9ºC
- 折射率：
- 1.566
- 蒸汽压：
- 4.07E-08mmHg at 25°C
17Β-羟基-3-甲氧基-1,3,5(10)-雌三烯 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KG7732000
- CHEMICAL NAME :
- Estra-1,3,5(10)-trien-17-beta-ol, 3-methoxy-
- CAS REGISTRY NUMBER :
- 1035-77-4
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C19-H26-O2
- MOLECULAR WEIGHT :
- 286.45
- WISWESSER LINE NOTATION :
- L E5 B666TTT&J E1 FQ OO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 2 mg/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E,
DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 49,193,1965
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 2500 ug/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - ovaries, fallopian tubes
Reproductive - Fertility - other measures of fertility
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E,
DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 49,193,1965
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 132 ug/kg
- SEX/DURATION :
- female 3 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E,
DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 47,444,1964
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 1050 ug/kg
- SEX/DURATION :
- female 3-9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E,
DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 47,444,1964
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 3 mg/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- 85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press,
1965 Volume(issue)/page/year: -,57,1965
17Β-羟基-3-甲氧基-1,3,5(10)-雌三烯 上游产品
17Β-羟基-3-甲氧基-1,3,5(10)-雌三烯 下游产品
(8S,9S,13S,14S,17S)-17-羟基-13-甲基- 2,4,6,7,8,9,11,12,14,15,16,17- 十二氢-1H -环戊烯并[一]苯基联苯胺-3-酮
雌二醇
16,17-二氢-3-甲氧基-17-甲基-15H-环戊二烯并(a)菲
3-甲氧基雌酮; 3-甲氧基-1,3,5(10)-雌甾三烯-17-酮
3-O-Methyl 17α-Estradiol
