(7S)-7-氨基-1,2,3,10-四甲氧基-6,7-二氢-5H-苯并[g]庚搭烯-9-酮
- 中文名称：
- (7S)-7-氨基-1,2,3,10-四甲氧基-6,7-二氢-5H-苯并[g]庚搭烯-9-酮
- 中文别名：
-
- 英文名称：
- Benzo[a]heptalen-9(5H)-one,7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-, (7S)-
- 英文别名：
- Benzo[a]heptalen-9(5H)-one,7-amino-6,7-dihydro-1,2,3,10-tetramethoxy-, (7S)-;
N-deacethylcolchicine;
N-deacetylcolchicine;
trimethylcolchicinic acid methyl ether;
deacetylcolchicine;
Desacetylcolchicine
- CAS No.：
- 3476-50-4
- 分 子 式：
-
C20H23NO5
- 分 子 量：
- 357.44
- 精确分子量：
- 357.15800
- PSA：
- 80.01000
- InChI：
- The Key: HFPMXDMZJUJZBX-AWEZNQCLSA-N3
- 安全术语：
- Poison by intraperitoneal and intramuscular routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also COLCHICINE and ETHERS.
- 分子结构式：
-
- SDS：
- 查看
(7S)-7-氨基-1,2,3,10-四甲氧基-6,7-二氢-5H-苯并[g]庚搭烯-9-酮 物化性质
- 密度：
- 1.25g/cm3
- 沸点：
- 626.6ºC at 760mmHg
- 闪点：
- 287ºC
- 折射率：
- 1.597
(7S)-7-氨基-1,2,3,10-四甲氧基-6,7-二氢-5H-苯并[g]庚搭烯-9-酮 安全信息
- 海关代码：
- 2922509090
- WGK_Germany：
- 3
德国有关水污染物质的分类清单
(7S)-7-氨基-1,2,3,10-四甲氧基-6,7-二氢-5H-苯并[g]庚搭烯-9-酮 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GH0785000
- CHEMICAL NAME :
- Colchicine, N-deacetyl-
- CAS REGISTRY NUMBER :
- 3476-50-4
- BEILSTEIN REFERENCE NO. :
- 2822162
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C20-H23-N-O5
- MOLECULAR WEIGHT :
- 357.44
- WISWESSER LINE NOTATION :
- L B677 MV&T&J CO1 DO1 EO1 JZ NO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - muscle weakness
Gastrointestinal - hypermotility, diarrhea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 35 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - muscle weakness
Gastrointestinal - hypermotility, diarrhea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 49 mg/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 46 mg/kg
- REFERENCE :
- CANCAR Cancer (Philadelphia). (Lippincott/Harper, Journal Fulfillment
Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1948-
Volume(issue)/page/year: 3,134,1950
(7S)-7-氨基-1,2,3,10-四甲氧基-6,7-二氢-5H-苯并[g]庚搭烯-9-酮 海关数据
中国海关编码：2922509090
- 概述：
- 2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
- 监管条件：
- A.入境货物通关单B.出境货物通关单
- 检验检疫：
- R.进口食品卫生监督检验S.出口食品卫生监督检验
- 摘要/Summary：
- 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
(7S)-7-氨基-1,2,3,10-四甲氧基-6,7-二氢-5H-苯并[g]庚搭烯-9-酮 上游产品
(7S)-7-氨基-1,2,3,10-四甲氧基-6,7-二氢-5H-苯并[g]庚搭烯-9-酮 下游产品
