制备方法

氢氧化亚铊TlOH在50℃下，在高真空中脱水时，则生成Tl2O。反应式如下：2TlOH→Tl2O+H2O但是需要注意的是：这种氢氧化物在空气中容易转化为碳酸盐和三氧化二铊Tl2O3。制法将碳酸亚铊Tl2CO3装到银制管状容器中，边抽真空(133.322×10-3Pa)边在600℃下连续加热数日，则在管中低温部分析出黑色升华物Tl2O。根据析出物的分析结果：Tl含量为95.13%(理论值为96.22%)，密度为10.2g/cm3。此外，还有用金属铊与三氧化二铊Tl2O3在560℃下长时间反应，可以得到接近于理论组成的Tl2O的方法。

合成制备方法

氢氧化亚铊TlOH在50℃下，在高真空中脱水时，则生成Tl₂O。反应式如下：

2TlOH→Tl₂O+H₂O

但是需要注意的是：这种氢氧化物在空气中容易转化为碳酸盐和三氧化二铊Tl₂O₃。

制法［42］将碳酸亚铊Tl₂CO₃装到银制管状容器中，边抽真空(133.322×10^-3Pa)边在600℃下连续加热数日，则在管中低温部分析出黑色升华物Tl2O。根据析出物的分析结果：Tl含量为95.13%(理论值为96.22%)，密度为10.2g/cm³。

此外，还有用金属铊与三氧化二铊Tl₂O₃在560℃下长时间反应，可以得到接近于理论组成的Tl₂O的方法。

用途简介

包装等级：

II

风险类别：

6.1(a)

WGK_Germany：

3
德国有关水污染物质的分类清单

危险类别码：

R22:Harmful if swallowed. R36/37/38:Irritating to eyes, respiratory system and skin .

安全说明：

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing .

RTECS号：

DO4562000

危险标志：

Xn,Xi

CHEMICAL IDENTIFICATION

RTECS NUMBER :

XG5970000

CHEMICAL NAME :

Thallium oxide

CAS REGISTRY NUMBER :

1314-12-1

LAST UPDATED :

199701

DATA ITEMS CITED :

8

MOLECULAR FORMULA :

O-Tl2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

40600 ug/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold Gastrointestinal - other changes Blood - hemorrhage

REFERENCE :

85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

75 mg/kg

TOXIC EFFECTS :

Brain and Coverings - encephalitis Gastrointestinal - other changes Skin and Appendages - hair

REFERENCE :

85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

31200 ug/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold Gastrointestinal - other changes Blood - hemorrhage

REFERENCE :

85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

31200 ug/kg

TOXIC EFFECTS :

Brain and Coverings - encephalitis Gastrointestinal - other changes Skin and Appendages - hair

REFERENCE :

85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

31200 ug/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold Gastrointestinal - other changes Blood - hemorrhage

REFERENCE :

85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

62400 ug/kg

TOXIC EFFECTS :

Brain and Coverings - encephalitis Gastrointestinal - other changes Skin and Appendages - hair

REFERENCE :

85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

40600 ug/kg

TOXIC EFFECTS :

Brain and Coverings - encephalitis Gastrointestinal - other changes Skin and Appendages - hair

REFERENCE :

85ECAN "Metal Toxicity in Mammals, Vol. 2: Chemical Toxicity of Metals and Metalloids," Venugopal, B., and T.D. Luckey, New York, Plenum Press, 1978 Volume(issue)/page/year: 2,101,1978

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:0

3.氢键受体数量:1

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积9.2

7.重原子数量:3

8.表面电荷:0

9.复杂度:2.8

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1