包装等级：

III

风险类别：

8

海关代码：

29211980

WGK_Germany：

2
德国有关水污染物质的分类清单

危险类别码：

R38;R41

安全说明：

S26-S28-S37/39

RTECS号：

RG4150000

安全标志：

S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
S36:穿戴合适的防护服装。

危险标志：

Xi:Irritant;

CHEMICAL IDENTIFICATION

RTECS NUMBER :

RG4150000

CHEMICAL NAME :

Octadecylamine

CAS REGISTRY NUMBER :

124-30-1

BEILSTEIN REFERENCE NO. :

0636111

LAST UPDATED :

199710

DATA ITEMS CITED :

9

MOLECULAR FORMULA :

C18-H39-N

MOLECULAR WEIGHT :

269.58

WISWESSER LINE NOTATION :

Z18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,439,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2395 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity)

REFERENCE :

GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 38(11),31,1973

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

3 gm/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity)

REFERENCE :

GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 38(11),31,1973

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

250 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

313 gm/kg/30W-C

TOXIC EFFECTS :

Related to Chronic Data - death

REFERENCE :

JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 14,196,1995 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83376 No. of Facilities: 166 (estimated) No. of Industries: 9 No. of Occupations: 9 No. of Employees: 1676 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83376 No. of Facilities: 634 (estimated) No. of Industries: 13 No. of Occupations: 11 No. of Employees: 4674 (estimated) No. of Female Employees: 363 (estimated)

毒理学数据：

皮肤/眼睛刺激性：标准德来塞实验

兔子皮肤接触，20mg/24HREACTION SEVERITY，中等反应；

兔子眼睛接触，20mg/24HREACTION SEVERITY，强烈反应；

急性毒性数据：大鼠腹腔LDLo：100mg/kg；小鼠腹腔LD50：315mg/kg

 

 

生态数据：

该物质对环境可能有危害，对水体应给予特别注意。

分子结构数据

1、   摩尔折射率：88.97

2、   摩尔体积（cm³/mol）：329.3

3、   等张比容（90.2K）：777.3

4、   表面张力（dyne/cm）：31.0

5、   极化率（10^-24cm³）：235.27

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:1

3.氢键受体数量:1

4.可旋转化学键数量:16

5.互变异构体数量:无

6.拓扑分子极性表面积26

7.重原子数量:19

8.表面电荷:0

9.复杂度:145

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

• 
  十八烷胺红外图谱(IR1)
• 
  十八烷胺红外图谱(IR2)
• 
  十八烷胺红外图谱(IR3)
• 
  十八烷胺质谱(MS)
• 
  十八烷胺核磁图(¹³CNMR)
• 
  十八烷胺核磁图(¹HNMR)