博来霉素A2
- 中文名称：
- 博来霉素A2
- 中文别名：
-
- 英文名称：
- Bleomycinamide,N1-[3-(dimethylsulfonio)propyl]-
- 英文别名：
- BLEOMYCIN A2;
Pingyangmycin A2;
Einecs 234-356-5;
Bleogin;
BLEMOYCIN AZ;
Zhengguangmycin A2;
Unii-13m89uea7w
- CAS No.：
- 11116-31-7
- 分 子 式：
-
C55H84N17O21S3
- 分 子 量：
- 1415.55
- 精确分子量：
- 1414.52000
- PSA：
- 708.85000
- EINECS：
- 234-356-5
- InChI：
- The Key: OYVAGSVQBOHSSS-VGWQMFASSA-O3
- 安全术语：
- Poison by intravenous and intraperitoneal routes. Noted for adverse pulmonary effects in humans. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See other bleomycin entries.
- 分子结构式：
-
- SDS：
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博来霉素A2 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EC5988500
- CHEMICAL NAME :
- Bleomycin A2
- CAS REGISTRY NUMBER :
- 11116-31-7
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 23
- MOLECULAR FORMULA :
- C55-H84-N17-O21-S3
- MOLECULAR WEIGHT :
- 1415.74
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 2143 ug/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - fibrosing alveolitis
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 130 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 108 mg/kg/36D-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - changes in lung weight
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - other Enzymes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 135 mg/kg/45D-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - changes in lung weight
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - other Enzymes
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 221,152,1982
推荐供应商
湖北恩星生物科技有限公司
博来霉素A2
- 联系人：邵经理
- 电 话：16621771607
- 手 机：16621771607
- Cas号：11116-31-7
- 包装：100kg,200kg,300kg,400kg,500kg
- 纯度：
- 价格：64.0元 - 100.0元
