西伐丁
- 中文名称：
- 西伐丁
- 中文别名：
- 西伐丁;
塞凡定
- 英文名称：
- Cevane-3,4,12,14,16,17,20-heptol,4,9-epoxy-, 3-[(2Z)-2-methyl-2-butenoate], (3b,4a,16b)-
- 英文别名：
- VERATRINE;
(z)-te;
CEVADINE;
Cevadene;
cevadin;
3-(2-methyl-2-butenoate);
utenoate)
- CAS No.：
- 62-59-9
- 分 子 式：
-
C32H49NO9
- 分 子 量：
- 591.82
- 精确分子量：
- 591.34100
- PSA：
- 160.15000
- EINECS：
- 200-545-6
- InChI：
- The Key: DBUCFOVFALNEOO-HWBIYQLFSA-N3
- 安全术语：
- Poison by intravenous, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
西伐丁 物化性质
- 密度：
- 1.41g/cm3
- 熔点：
- 213.5ºC (with decomposition)
- 沸点：
- 733.3ºC at 760 mmHg
- 闪点：
- 397.3ºC
- 折射率：
- 1.647
- 存储条件/存储方法：
- 库房低温通风干燥,与食品原料分开存放
西伐丁 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FL5600000
- CHEMICAL NAME :
- Cevane-3-beta,4-beta,12,14,16-beta,17,20-heptol,
4,9-epoxy-, 3-(2-methylcrotonate), (Z)-
- CAS REGISTRY NUMBER :
- 62-59-9
- BEILSTEIN REFERENCE NO. :
- 0072445
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C32-H49-N-O9
- MOLECULAR WEIGHT :
- 591.82
- WISWESSER LINE NOTATION :
- T J6 H6 E6 D5665/TC& 3ATU C& ON TX C&OTJ EQ GQ IQ I1
M1 RQ U1 A&OV1UY1&1 B&Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
Volume(issue)/page/year: 76,847,1951
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4900 ug/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 113,89,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
(usually neuromuscular blockage)
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville
Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year:
26,383,1946
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 116 mg/kg
- TOXIC EFFECTS :
- Cardiac - arrhythmias (including changes in conduction)
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 120,412,1957
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
(usually neuromuscular blockage)
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville
Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year:
26,383,1946
推荐供应商
山东默派生物科技有限公司
西伐丁
- 联系人：张经理
- 电 话：13070690626
- 手 机：13070690626
- Cas号：62-59-9
- 包装：100kg
- 纯度：99%
- 价格：100.0元
