联苯吡胺
- 中文名称：
- 联苯吡胺
- 中文别名：
- 联苯吡胺
- 英文名称：
- [1,1'-Biphenyl]-4-acetamide,N-2-pyridinyl-
- 英文别名：
- difenpiramide;
Z-876;
2-Biphenylyl-N-pyridylacetamide;
2-(4-phenylphenyl)-N-pyridin-2-ylacetamide;
Pyridyl-biphenylyl-acetamide;
Difenax;
Acetamide,2-biphenylyl-N-pyridyl;
Difenpiramide;
Diphenpyramide
- CAS No.：
- 51484-40-3
- 分 子 式：
-
C19H16N2O
- 分 子 量：
- 288.34314
- 精确分子量：
- 288.12600
- PSA：
- 41.99000
- EINECS：
- 257-235-9
- InChI：
- The Key: PWHROYKAGRUWDQ-UHFFFAOYSA-N3
- 分子结构式：
-
- SDS：
- 查看
联苯吡胺 物化性质
- 密度：
- 1.192g/cm3
- 沸点：
- 549ºC at 760 mmHg
- 闪点：
- 285.8ºC
- 折射率：
- 1.645
联苯吡胺 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AB4549000
- CHEMICAL NAME :
- Acetamide, 2-biphenylyl-N-pyridyl-
- CAS REGISTRY NUMBER :
- 51484-40-3
- BEILSTEIN REFERENCE NO. :
- 0483768
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C19-H16-N2-O
- MOLECULAR WEIGHT :
- 288.37
- WISWESSER LINE NOTATION :
- T6NJ BMV1R DR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1857 mg/kg
- TOXIC EFFECTS :
- Biochemical - Metabolism (Intermediary) - effect on inflammation or
mediation of inflammation
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,2086,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1396 mg/kg
- TOXIC EFFECTS :
- Biochemical - Metabolism (Intermediary) - effect on inflammation or
mediation of inflammation
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,2086,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2590 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,2086,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1471 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,2086,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Behavioral - analgesia
Nutritional and Gross Metabolic - body temperature decrease
Biochemical - Metabolism (Intermediary) - effect on inflammation or
mediation of inflammation
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica,
Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year:
118,729,1979
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Behavioral - analgesia
Nutritional and Gross Metabolic - body temperature decrease
Biochemical - Metabolism (Intermediary) - effect on inflammation or
mediation of inflammation
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica,
Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year:
118,729,1979
联苯吡胺 海关数据
中国海关编码：2933399090
- 概述：
- 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
