(+-)-前列腺素 F2-alpha
- 中文名称：
- (+-)-前列腺素 F2-alpha
- 中文别名：
-
- 英文名称：
- Prosta-5,13-dien-1-oicacid, 9,11,15-trihydroxy-, (5Z,9a,11a,13E,15S)-(?à)- (9CI)
- 英文别名：
- (5E,13E)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic acid;
9-oxo-11S,15S-dihydroxy-13E-prostaenoic acid;
11-epi-PGE1;
11-Epiprostaglandin E1
- CAS No.：
- 23518-25-4
- 分 子 式：
-
C20H34O5
- 分 子 量：
- 354.54
- 精确分子量：
- 354.24100
- PSA：
- 97.99000
- InChI：
- The Key: PXGPLTODNUVGFL-BRIYLRKRSA-N3
- 风险术语：
- 20-35
- 安全术语：
- Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. See also PROSTAGLANDIN A1; PROSTAGLANDIN D2; PROSTAGLANDIN E1; PROSTAGLANDIN E2 SODIUM SALT; PROSTAGLANDIN F1-α; PROSTAGLANDIN F2-α; PROSTAGLANDIN F2-α-THAM.
- 分子结构式：
-
- SDS：
- 查看
(+-)-前列腺素 F2-alpha 物化性质
- 密度：
- 1.153g/cm3
- 沸点：
- 531ºC at 760 mmHg
- 闪点：
- 289ºC
- 折射率：
- 1.569
- 蒸汽压：
- 1.71E-13mmHg at 25°C
(+-)-前列腺素 F2-alpha 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MJ9656000
- CHEMICAL NAME :
- 5-Heptenoic acid,
7-(3,5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-
, dl-
- CAS REGISTRY NUMBER :
- 23518-25-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C20-H34-O5
- MOLECULAR WEIGHT :
- 354.54
- WISWESSER LINE NOTATION :
- L5TJ AQ B2U4VQ C1U1YQ5 DQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 32 mg/kg
- SEX/DURATION :
- female 4-7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32,
Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939-
Volume(issue)/page/year: 53,201,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 20 mg/kg
- SEX/DURATION :
- female 4-7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
- REFERENCE :
- PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022)
V.1- 1972- Volume(issue)/page/year: 2,375,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 9 mg/kg
- SEX/DURATION :
- female 4-6 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
Reproductive - Fertility - other measures of fertility
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot,
POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960-
Volume(issue)/page/year: 28,451,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 36 mg/kg
- SEX/DURATION :
- female 4-6 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32,
Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939-
Volume(issue)/page/year: 53,201,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 600 ug/kg
- SEX/DURATION :
- female 4-6 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
- REFERENCE :
- JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32,
Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939-
Volume(issue)/page/year: 53,201,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 400 ug/kg
- SEX/DURATION :
- female 4 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- REFERENCE :
- JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32,
Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939-
Volume(issue)/page/year: 53,201,1972
