氟化钠
- 中文名称：
- 氟化钠
- 中文别名：
- 氟化钠;
Sodiumhydrogensulfate;
sulfuricacid,monosodiumsalt;
sodium hydrogen sulphate;
sodium hydrogensulfate;
Sodium bisulfate;
TRICHLORO-2,4,6-TRIAMINO-SYM-TRIAZINE;
Trichloromelamine;
CGMP, GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE;
2-amino-9-(2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl)-3,9-dihydro-6H-purin-6-one;
2-amino-9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-3,9-dihydro-6H-purin-6-one;
- 英文名称：
- Sodium fluoride
- 英文别名：
- sodium fluoride;
Sodium fluoride
- CAS No.：
- 7681-49-4
- 分 子 式：
-
NaF
- 分 子 量：
- 41.99
- 精确分子量：
- 41.98820
- PSA：
- 0.00000
- MDL：
- MFCD07370792
- EINECS：
- 231-667-8
- InChI：
- InChI=1/FH.Na/h1H;/q;+1/p-13
- 危险品标志：
-
T
T- 分子结构式：
-
- SDS：
- 查看
氟化钠 制备方法及用途
制备方法
-
1.熔浸法 将萤石、纯碱和石英砂,在高温(800～900℃)下煅烧,然后用水浸取,再经蒸发、结晶、干燥得成品。反应方程式如下: 2.中和法 用纯碱或烧碱中和氢氟酸而得,反应方程式如下: 在中和锅内用母液溶解纯碱,然后加入30%的氢氟酸中和至pH值8～9,且有CO2气体逸出为止,氢氟酸中往往含有氟硅酸杂质,中和后生成氟硅酸钠;在90～95℃:下加热1h,氟硅酸钠即分解:反应方程式如下: 中和过程中pH值不得低于8,不然氟硅酸钠难被碱分解,中和液静置1h,清液经浓缩后冷却析出氟化钠结晶,再经离心分离、干燥、粉碎得成品。 3.氟硅酸钠法 由湿法磷酸和磷肥副产的氟硅酸,按常规方法可制得99.87%的氟硅酸钠。在84～95℃和0.15MPa的条件下反应160～180min、过量5%～8%的碱性溶液(pH值为8～9)中,生成氟化钠。反应方程式如下: 中和液静置澄清后,清液经蒸发浓缩、冷却结晶,分离后用50～60℃的热水洗涤,间接干燥得成品。 4.工业上制备氟化钠由氟硅酸钠作原料。在聚乙烯的烧杯中将45g氟硅酸钠溶于50g水中,加热至80℃,在搅拌下缓缓加入50.7g碳酸钠,接着加入49% NaOH水溶液39g,加热至95℃以上,即有氟化钠沉淀生成,抽滤,用水充分洗涤数遍,干燥。可得58g氟化钠。纯度可达99%。 5.制取高纯度的氟化钠,可使氢氟酸与碳酸钠、碳酸氢钠或氢氧化钠作用。在聚乙烯的烧杯中,加入50g 46%的氢氟酸,加水42g稀释,使浓度为25%。加计算量的NaOH水溶液,氟化钠沉淀立即生成,吸滤,用水充分洗涤。在烘箱中于110℃烘干。为制取极纯品,可用高纯度的氢氟酸与碳酸氢钠中和,至弱酸性即达终点,沉淀在550～650℃下干燥即可。
合成制备方法
1.熔浸法
将萤石、纯碱和石英砂，在高温(800～900℃)下煅烧，然后用水浸取，再经蒸发、结晶、干燥得成品。反应方程式如下：
2.中和法
用纯碱或烧碱中和氢氟酸而得，反应方程式如下：
在中和锅内用母液溶解纯碱，然后加入30%的氢氟酸中和至pH值8～9，且有CO2气体逸出为止，氢氟酸中往往含有氟硅酸杂质，中和后生成氟硅酸钠；在90～95℃：下加热1h，氟硅酸钠即分解：反应方程式如下：
中和过程中pH值不得低于8，不然氟硅酸钠难被碱分解，中和液静置1h，清液经浓缩后冷却析出氟化钠结晶，再经离心分离、干燥、粉碎得成品。
3.氟硅酸钠法
由湿法磷酸和磷肥副产的氟硅酸，按常规方法可制得99.87%的氟硅酸钠。在84～95℃和0.15MPa的条件下反应160～180min、过量5%～8%的碱性溶液(pH值为8～9)中，生成氟化钠。反应方程式如下：
中和液静置澄清后，清液经蒸发浓缩、冷却结晶，分离后用50～60℃的热水洗涤，间接干燥得成品。
4.工业上制备氟化钠由氟硅酸钠作原料。在聚乙烯的烧杯中将45g氟硅酸钠溶于50g水中，加热至80℃，在搅拌下缓缓加入50.7g碳酸钠，接着加入49% NaOH水溶液39g，加热至95℃以上，即有氟化钠沉淀生成，抽滤，用水充分洗涤数遍，干燥。可得58g氟化钠。纯度可达99%。
5.制取高纯度的氟化钠，可使氢氟酸与碳酸钠、碳酸氢钠或氢氧化钠作用。在聚乙烯的烧杯中，加入50g 46%的氢氟酸，加水42g稀释，使浓度为25%。加计算量的NaOH水溶液，氟化钠沉淀立即生成，吸滤，用水充分洗涤。在烘箱中于110℃烘干。为制取极纯品，可用高纯度的氢氟酸与碳酸氢钠中和，至弱酸性即达终点，沉淀在550～650℃下干燥即可。
用途简介
-
氟化钠主要涂装工业中作磷化促进剂，使磷化液稳定，磷化细化，改良磷化膜性能。铝及其合金磷化中封闭具有危害性很大的负催化作用的Al3+，使磷化顺利进行木材防腐剂、农业杀虫剂、酿造业杀菌剂、医药防腐剂、焊接助焊剂、碱性锌酸盐镀锌添加剂及搪瓷、造纸业等。
用途
1.主要用于机械刀片和刨刀的镶钢以增强焊接强度。其次用作木材防腐剂、酿造业杀菌剂，农业杀虫剂(须染上蓝色)、医用防腐剂、焊接助熔剂、饮水的氟处理剂。还用于其他氟化物和酪蛋白胶、氟化钠牙膏的生产，以及黏结剂、造纸和冶金行业。在元素氟生产中，用于除去微量氟化氢。此外，还用于搪瓷和制药等工业。
2.钢铁分析。光电比色法测定磷。点滴分析测定钪。血液检验。掩蔽剂。助熔剂。
3.作食品强化剂。我国规定可用于食盐，最大使用量为0.1g/kg。
4.用作分析试剂，如生成配合物作掩蔽剂，生成不溶性氟化物作沉淀剂。还作助熔剂和防腐剂。
5.用作络合水中的铁离子，减小铁对胶黏剂基料等聚合反应的影响。也可用木材及医药防腐剂、农业杀虫剂（须染上蓝色）、酿造业杀菌剂、饮水氟处理剂、焊接助熔剂等。也用作制造其他氟化物、搪瓷、含氟牙膏及药物等的原料。也可将本品与其他盐类制成浆膏，用于修复电杆及枕木。用作防腐剂时，常与铬盐、砷盐、五氯酚钠或二硝基苯酚等并用，具有协同增效作用。
6.用作牙膏的主要防龋剂、农业杀虫剂、木材防腐剂和金属助溶剂等。
7.在铝及合金的碱性纹理蚀刻中，添加适量的氟化钾可增加蚀刻表面的白度，其用作铝及合金钝化及磷化中的活化剂，可促进钝化膜和磷化膜的形成，但浓度过高会使膜层疏松，甚至不能成膜。氟化钠用于电镀镍、锡和化学镀镍、镀锌的低铬酸的钝化、铝和镁合金的化学氧化以及钢铁磷化等溶液中。
8.用作杀虫剂、木材防腐剂。[20]
氟化钠 物化性质
- 外观与性状：
- 白色无气味的粉末或晶体
- 密度：
- 1.02 g/mL at 20 °C
- 熔点：
- 993 °C(lit.)
- 沸点：
- 1700 °C
- 闪点：
- 1704°C
- 水溶解性：
- 4 g/100 mL (25 ºC)
- 折射率：
- 1.336
- 存储条件/存储方法：
- 库房通风低温干燥,与氧化剂、食品添加剂分开存放
- 稳定性相关：
1.有毒，有腐蚀性。在100g水中的溶解度为4.0g（15℃），5.0g（100℃），不溶于乙醇。在水溶液中部分水解，故水溶液显碱性，饱和溶液的pH值为7.4。
2.稳定性[16] 稳定
3.禁配物[17] 强酸
4.聚合危害[18] 不聚合
- 其它信息：
1.性状：白色粉末或结晶，无臭。[1]
2.pH值：7.4（新配制的饱和溶液）[2]
3.熔点（℃）：986.9~996[3]
4.沸点（℃）：1695~1700[4]
5.相对密度（水=1）：2.56~2.79[5]
6.饱和蒸气压（kPa）：0.13（1077℃）[6]
7.辛醇/水分配系数：-0.77[7]
8.溶解性：溶于水，微溶于乙醇。[8]
氟化钠 安全信息
- 包装等级：
- III
- 风险类别：
- 6.1
- 海关代码：
- 2826192010
- WGK_Germany：
- 1
德国有关水污染物质的分类清单 - 危险类别码：
- R25;R32;R36/38
- 安全说明：
- S23-S24/25-S45-S36-S22
- RTECS号：
- WB0350000
- 安全标志：
- S22:不要吸入粉尘。
S36:穿戴合适的防护服装。
S45:出现意外或者感到不适，立刻到医生那里寻求帮助（最好带去产品容器标签）。 - 危险标志：
- T:Toxic
氟化钠 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WB0350000
- CHEMICAL NAME :
- Sodium fluoride
- CAS REGISTRY NUMBER :
- 7681-49-4
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 152
- MOLECULAR FORMULA :
- F-Na
- MOLECULAR WEIGHT :
- 41.99
- WISWESSER LINE NOTATION :
- NA F
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 90 mg/kg
- TOXIC EFFECTS :
- Behavioral - fluid intake Behavioral - muscle weakness Gastrointestinal - nausea or vomiting
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 360 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 7 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Lungs, Thorax, or Respiration - cyanosis
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 1662 mg/kg
- TOXIC EFFECTS :
- Cardiac - EKG changes not diagnostic of specified effects Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - nausea or vomiting
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 214 ug/kg
- TOXIC EFFECTS :
- Behavioral - headache Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 71 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Musculoskeletal - changes in teeth and supporting structures Musculoskeletal - other changes
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intradermal
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 14 ug/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - paresthesis Immunological Including Allergic - increased immune response
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 52 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 22 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 175 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 26 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - tumors Sense Organs and Special Senses (Eye) - effect, not otherwise specified Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 57 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 38 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 115 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50830 ug/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 155 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 26600 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 14 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 448 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - domestic
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 110 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 420 mg/kg/6W-C
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Behavioral - somnolence (general depressed activity) Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg/5D-C
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 603 mg/kg/26W-I
- TOXIC EFFECTS :
- Musculoskeletal - other changes Nutritional and Gross Metabolic - changes in calcium Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1500 mg/kg/60D-I
- TOXIC EFFECTS :
- Gastrointestinal - other changes Biochemical - Metabolism (Intermediary) - lipids including transport
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 mg/kg/5H/17W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes Musculoskeletal - changes in teeth and supporting structures Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 105 mg/kg/10D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 160 mg/kg/14D-C
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 21840 mg/kg/26W-C
- TOXIC EFFECTS :
- Musculoskeletal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 402 mg/kg/35D-I
- TOXIC EFFECTS :
- Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in erythrocyte (RBC) count Blood - changes in leukocyte (WBC) count
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 5460 mg/kg/78W-I
- TOXIC EFFECTS :
- Gastrointestinal - malabsorption Blood - other changes Nutritional and Gross Metabolic - changes in calcium
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 6930 mg/kg/99W-I
- TOXIC EFFECTS :
- Musculoskeletal - other changes Nutritional and Gross Metabolic - changes in calcium Nutritional and Gross Metabolic - changes in phosphorus
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 3650 mg/kg/1Y-I
- TOXIC EFFECTS :
- Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Blood - changes in leukocyte (WBC) count
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1327 mg/kg/30D-I
- TOXIC EFFECTS :
- Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12617 mg/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - thyroid tumors Musculoskeletal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 14 mg/kg/43W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 140 mg/kg/43W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4200 mg/kg/30W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2190 mg/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4217 mg/kg/30W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4242 mg/kg/30W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4368 mg/kg/30W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 87 gm/kg/97W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 150 mg/kg
- SEX/DURATION :
- male 30 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 221 mg/kg
- SEX/DURATION :
- female 1-20 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 240 mg/kg
- SEX/DURATION :
- female 11-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 128 mg/kg
- SEX/DURATION :
- female 85 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - behavioral
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 255 mg/kg
- SEX/DURATION :
- female 85 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 9 mg/kg
- SEX/DURATION :
- female 10-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord) Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 90 mg/kg
- SEX/DURATION :
- female 10-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord) Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intratesticular
- DOSE :
- 400 ug/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1240 mg/kg
- SEX/DURATION :
- male 8 week(s) pre-mating female 8 week(s) pre-mating - 5 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) Reproductive - Effects on Newborn - stillbirth
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 620 mg/kg
- SEX/DURATION :
- multigenerations
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 5600 ug/kg
- SEX/DURATION :
- lactating female 14 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - skin and skin appendages
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 300 ng/kg
- SEX/DURATION :
- male 30 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 8800 mg/kg
- SEX/DURATION :
- male 2.4 year(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TYPE OF TEST :
- Micronucleus test
- TYPE OF TEST :
- Micronucleus test
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Sister chromatid exchange
- TYPE OF TEST :
- Sperm Morphology
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Mammal - species unspecified Lung
- REFERENCE :
- HKXUDL Huanjing Kexue Xuebao. Environmental Sciences Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1981- Volume(issue)/page/year: 3,94,1983 *** REVIEWS *** ACGIH TLV-TWA 2.5 mg(F)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,237,1982 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 27,237,1982 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,208,1987 TOXICOLOGY REVIEW ADVPA3 Advances in Pharmacology. (New York, NY) V.1-6, 1962-68. For publisher information, see AVPCAQ. Volume(issue)/page/year: 4,263,1966 TOXICOLOGY REVIEW AMSSAQ Acta Medica Scandinavica, Supplement. (Almqvist & Wiksell, POB 45150, S-10430 Stockholm, Sweden) No.1-730, 1921-88. Volume(issue)/page/year: 400,5,1963 TOXICOLOGY REVIEW FNSCA6 Forensic Science. (Lausanne, Switzerland) V.1-11, 1972-78. For pub lisher information, see FSINDR. Volume(issue)/page/year: 2,67,1973 TOXICOLOGY REVIEW IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.18-42, 1949-73. For publisher information, see IOHSA5. Volume(issue)/page/year: 19,535,1950 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 MSHA STANDARD-air:TWA 2.5 mg(F)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,116,1971 OSHA PEL (Gen Indu):8H TWA 2.5 mg(F)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 2.5 mg(F)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 2.5 mg(F)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 2.5 mg(F)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 2.5 mg(F)/m3 JAN 1993 OEL-BELGIUM:TWA 2.5 mg(F)/m3 JAN 1993 OEL-DENMARK:TWA 2.5 mg(F)/m3 JAN 1993 OEL-FINLAND:TWA 2.5 mg(F)/m3 JAN 1993 OEL-FRANCE:TWA 2 mg/m3 JAN 1993 OEL-FRANCE:TWA 2.5 mg(F)/m3 JAN 1993 OEL-GERMANY:TWA 2.5 mg(F)/m3 JAN 1993 OEL-HUNGARY:TWA 1 mg(F)/m3;STEL 2 mg(F)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 2.5 mg(F)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 2.5 mg(F)/m3 JAN 1993 OEL-POLAND:TWA 1 mg(F)/m3 JAN 1993 OEL-RUSSIA:TWA 0.2 mg/m3;STEL 1 mg/m3 JAN 1993 OEL-SWEDEN:TWA 2 mg(F)/m3 JAN 1993 OEL-SWITZERLAND:TWA 1.8 ppm (1.5 mg(F)/m3);STEL 9.0 ppm JAN 1993 OEL-THAILAND:TWA 2.5 mg(F)/m3 JAN 1993 OEL-TURKEY:TWA 2.5 mg(F)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 2.5 mg(F)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO FLUORIDES, INORGANIC-air:10H TWA 2.5 mg(F)/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84425 No. of Facilities: 3763 (estimated) No. of Industries: 50 No. of Occupations: 50 No. of Employees: 25059 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84425 No. of Facilities: 3970 (estimated) No. of Industries: 83 No. of Occupations: 69 No. of Employees: 84776 (estimated) No. of Female Employees: 26602 (estimated)
- 毒理学数据：
1.急性毒性[9] LD50：52mg/kg（大鼠经口）；57mg/kg（小鼠经口）
2.刺激性[10] 家兔经眼：20mg（24h），中度刺激。
3.亚急性与慢性毒性[11] 大鼠以含氟化物7~9ppm的饲料连续喂养可引起牙钙化障碍，剂量增大则致骨骼改变。
4.致突变性[12] 微生物致突变：鼠伤寒沙门菌1mg/皿。细胞遗传学分析：人成纤维细胞20mg/L。程序外DNA合成：人成纤维细胞100mg/L。DNA抑制：人成纤维细胞100mg/L。
5.致畸性[13] 大鼠孕后11~14d经口给予最低中毒剂量（TDLo）240mg/kg，致肌肉骨骼系统发育畸形。雌性大鼠交配前85d，经口给予最低中毒剂量（TDLo）255mg/kg，致中枢神经系统发育畸形。大鼠多代经口给予最低中毒剂量（TDLo）3.4mg/kg，致泌尿生殖系统发育畸形。
6.致癌性[14] IARC致癌性评论：G3，对人及动物致癌性证据不足。
7.其他[15] 大鼠经口最低中毒剂量（TDLo）：240mg/kg（孕11~14d），肌肉骨骼发育异常。
- 生态数据：
1.生态毒性 暂无资料
2.生物降解性 暂无资料
3.非生物降解性 暂无资料
氟化钠 MSDS
| 国标编号: | 61513 |
| ＣＡＳ: | 7681-49-4 |
| 中文名称: | 氟化钠 |
| 英文名称: | sodium fluoride |
| 别 名: | |
| 分子式: | NaF |
| 分子量: | 42.00 |
| 熔 点: | 993℃ |
| 密 度: | 相对密度(水=1)2.56 |
| 蒸汽压: | |
| 溶解性: | 溶于水，微溶于醇 |
| 稳定性: | 稳定 |
| 外观与性状: | 白色粉末或结晶，无臭 |
| 危险标记: | 15(有害品) |
| 用 途: | 用作杀虫剂、木材防腐剂 |
2.对环境的影响
该物质对环境可能有危害，对水体应给予特别注意。
一、健康危害
侵入途径：吸入、食入。 健康危害：急性中毒：多为误服所致。服后立即出现剧烈恶心、呕吐、腹痛、腹泻。重者休克、呼吸困难、紫绀。可能于2～4小时内死亡。部分患者出现荨麻疹，吞咽肌麻痹，手足抽搐或四肢肌肉痉挛。氟化钠粉尘和蒸气对皮肤有刺激作用，可以引起皮炎。 慢性影响：可引起氟骨症。
二、毒理学资料及环境行为
刺激性：家兔经皮：500mg(24小时)，重度刺激。 亚急性和慢性毒性：大鼠以含氟化物7～9ppm的饲料连续喂养可引起牙钙化障碍，剂量增大则致骨骼改变。 致突变性：微生物致突变：鼠伤寒沙门氏菌1mg/皿。细胞遗传学分析：人成纤维细胞20mg/L。 生死毒性：大鼠经口最低中毒剂量(TDL0)：240mg/kg(孕11～14天)，肌肉骨骼发育异常。 致癌性：IARC致癌性评论：人不明确。
危险特性：未有特殊的燃烧爆炸特性。 燃烧(分解)产物：氟化氢。
3.现场应急监测方法
速测管法；离子选择电极法
4.实验室监测方法
离子选择性电极法(GB7484-87，水质，氟化物)氟试剂分光光度法(GB7483-87，水质，氟化物)滤膜氟离子选择电极法(GB/T15434-95，空气，氟化物)
5.环境标准
| 中 国 (TJ36-79) | 车间空气中有害物质的最高容许浓度 | 1mg/m3[F] |
| 中 国 (TJ36-79) | 居住区大气中有害物质的最高容许浓度(氟化物) | 0.02mg/m3(一次值)；0.007mg/m3(日均值) |
| 中国(GB16297-1996) | 大气污染物综合排放标准(氟化物) |
①最高允许排放浓度(mg/m3) 9～90(表2)；11～100(表1) ②最高允许排放速率(kg/h) 二级0.10～4.2(表2)；0.12～4.9(表1) 三级0.15～6.3(表2)；0.18～7.5(表1) ③无组织排放监控浓度限值(mg/m3) 0.02(表2)；0.02(表1) |
| 中国(GB5048-92) | 农田灌溉水质标准(氟化物) | 2.0～3.0mg/L(水作，旱作，蔬菜) |
| 中国(GB11607-89) | 渔业水质标准 | 1mg/L(氟化物) |
| 中国(GB5749-85) | 生活饮用水卫生标准 | 1.0mg/L(氟化物) |
| 中国(GB/T14848-93) | 地下水质量标准(mg/L) | I类1.0；II类1.0；III类1.0；IV类2.0；V类2.0以上(氟化物) |
| 中国(GHZB1-1999) |
地表水环境质量标准(mg/L) |
I类1.0以下 ；II类1.0；III类1.0 ；IV类1.5； V类1.5(氟化物) |
|
中国(GB8978-1996) |
污水综合排放标准(mg/L) |
一级10；二级10～20；三级20～30(氟化物) |
| 中国(GB5058.3-1996) | 固体废弃物浸出毒性鉴别标准值 | 50mg/L(氟化物) |
6.应急处理处置方法
一、泄漏应急处理
隔离泄漏污染区，周围设警告标志，建议应急处理人员戴好防毒面具，穿相应的工作服。不要直接接触泄漏物。避免扬尘，用洁净的铲子收集于干燥、洁净、有盖的容器中。如大量泄漏收集回收或运至废物处理场所处置。
二、防护措施
呼吸系统防护：空气中浓度超标时，应该佩戴防毒口罩。紧急事态抢救或逃生时，建议佩戴自给式呼吸器。 眼睛防护：戴化学安全防护眼镜。 防护服：穿相应的防护服。 手防护：戴防化学品手套。 其它：工作现场禁止吸烟、进食和饮水。工作后，淋浴更衣。工作服不要带至非作业场所。单独存放被毒物污染的衣服，洗后备用。保持良好的卫生习惯。
三、急救措施
皮肤接触：脱去被污染的衣着，立即用流动清水彻底冲洗。 眼睛接触：立即提起眼睑，用流动清水冲洗10分钟或用2%碳酸氢钠溶液冲洗。 吸入：脱离现场至空气新鲜处。必要时进行人工呼吸。就医。 食入：患者清醒时给饮大量温水，催吐，尽快洗胃。就医。
灭火方法：不燃。火场周围可用的灭火介质。
氟化钠 分子结构与计算化学数据
分子结构数据
1、摩尔折射率：无可用的
2、摩尔体积（cm3/mol）：无可用的
3、等张比容（90.2K）：无可用的
4、表面张力（dyne/cm）：无可用的
5、介电常数：无可用的
6、极化率：无可用的
7、单一同位素质量：41.988173 Da
8、标称质量：42 Da
9、平均质量：41.9882 Da
计算化学数据
1.疏水参数计算参考值（XlogP）:无
2.氢键供体数量:0
3.氢键受体数量:1
4.可旋转化学键数量:0
5.互变异构体数量:无
6.拓扑分子极性表面积0
7.重原子数量:2
8.表面电荷:0
9.复杂度:2
10.同位素原子数量:0
11.确定原子立构中心数量:0
12.不确定原子立构中心数量:0
13.确定化学键立构中心数量:0
14.不确定化学键立构中心数量:0
15.共价键单元数量:2
