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2-氯甲苯

中文名称：: 2-氯甲苯

中文别名：: 2-氯甲苯;
邻氯甲苯

英文名称：: 2-Chlorotoluene

英文别名：: 2-Chlorotoluene;
markiertes Capsaicin;
Methylcapsaicin;
mono-chlorotoluene;
O-Methyl-capsaicin;
2-tolyl chloride;
o-methylchlorobenzne;
o-chlorotoluene;
6-Nonenamide,N-((3,4-dimethoxyphenyl)methyl)-8-methyl-,(E);
o-tolyl chloride;
ortho-chlorotoluene

CAS No.：: 95-49-8

分子式：: C₇H₇Cl

分子量：: 126.58

精确分子量：: 126.02400

PSA：: 0.00000

MDL：: MFCD00000562

EINECS：: 202-424-3

BRN：: 1904175

危险品标志：: XnN

风险术语：: R20; R51/53;

安全术语：: S24/25; S61;

分子结构式：

SDS：: 查看

2-氯甲苯毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XS9000000

CHEMICAL NAME :: Toluene, o-chloro-

CAS REGISTRY NUMBER :: 95-49-8

BEILSTEIN REFERENCE NO. :: 1904175

LAST UPDATED :: 199712

DATA ITEMS CITED :: 28

MOLECULAR FORMULA :: C7-H7-Cl

MOLECULAR WEIGHT :: 126.59

WISWESSER LINE NOTATION :: GR B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3900 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - tremor Behavioral - excitement

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(10),56,1981

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4400 ppm

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: 85INA8 "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 6,308,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(12),64,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - tremor Behavioral - excitement

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(10),56,1981

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4400 ppm

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: 85INA8 "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 6,308,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(12),64,1980

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 4400 ppm

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: 85INA8 "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 6,308,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - excitement Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 46(2),67,1981 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 35910 mg/kg/9W-I

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 46(2),67,1981 *** REVIEWS *** ACGIH TLV-TWA 259 mg/m3 (50 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 50 ppm (250 mg/m3);STEL 75 ppm (375 mg/m3) JAN 1993 OEL-BELGIUM:TWA 50 ppm (259 mg/m3);STEL 75 ppm (388 mg/m3) JAN 1993 OEL-DENMARK:TWA 50 ppm (250 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 50 ppm (260 mg/m3);STEL 75 ppm (390 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 50 ppm (250 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 50 ppm (250 mg/m3);Skin JAN 1993 OEL-RUSSIA:STEL 10 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 50 ppm (250 mg/m3);Skin JAN 1993 OEL-UNITED KINGDOM:TWA 50 ppm (250 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO o-CHLOROTOLUENE-air:10H TWA 50 ppm;STEL 75 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1254 No. of Facilities: 62 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 11617 (estimated) No. of Female Employees: 963 (estimated)

毒理学数据：

1、急性毒性：大鼠经口LD50：3900mg/kg

小鼠经口LD5O：2500mg/kg

大鼠吸入LCLO：4400ppm

小鼠吸入LCLO：4400ppm

豚鼠吸入LCLO：4400ppm

2、生理作用与氯苯相似，主要经呼吸道吸收，对黏膜（尤以眼结膜）有刺激作用。对中枢神经和内脏都有损害。皮肤接触可引起红斑和大疱乃至湿疹。工作场所最高容许浓度为250mg/m3（美国）。

生态数据：: 该物质对环境有危害，建议不要让其进入环境。应特别注意对水体的污染。

武汉吉鑫益邦生物科技有限公司

邻氯甲苯

联系人：周美玲
电话：027-59768650
手机：15629090339

Cas号：95-49-8
包装：1kg,25kg,200kg,400kg,500kg
纯度：0-99%
价格：洽谈

2-氯甲苯

2-氯甲苯制备方法及用途

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2-氯甲苯 MSDS

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计算化学数据

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推荐供应商

武汉吉鑫益邦生物科技有限公司

邻氯甲苯

2-氯甲苯制备方法及用途

2-氯甲苯物化性质

2-氯甲苯安全信息

2-氯甲苯毒理性

2-氯甲苯分子结构与计算化学数据

2-氯甲苯上游产品

2-氯甲苯下游产品

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