美雄烷
- 中文名称：
- 美雄烷
- 中文别名：
- 美雄烷
- 英文名称：
- Androstane,2,3-epithio-17-[(1-methoxycyclopentyl)oxy]-, (2a,3a,5a,17b)-
- 英文别名：
- Mepitiostane;
2,3-Epithio-1H-cyclopenta[a]phenanthrene,androstane deriv.;
2a,3a-Epithio-17b-(1-methoxycyclopentyloxy)-5a-androstane;
2a,3a-Epithio-17b-(cyclopentylmethoxy)-5a-androstane;
2a,3a-Epithio-5a-androstan-17b-yl 1-methoxycyclopentyl ether
- CAS No.：
- 21362-69-6
- 分 子 式：
-
C25H40O2S
- 分 子 量：
- 404.71
- 精确分子量：
- 404.27500
- PSA：
- 43.76000
- 安全术语：
- Human systemic effects by ingestion: dermatitis, liver changes, and transaminase activity. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx.
- 分子结构式：
-
- SDS：
- 查看
美雄烷 物化性质
- 密度：
- 1.13g/cm3
- 沸点：
- 485.2ºC at 760mmHg
- 闪点：
- 247.2ºC
- 折射率：
- 1.568
- 蒸汽压：
- 0mmHg at 25°C
美雄烷 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BV8044500
- CHEMICAL NAME :
- 5-alpha-Androstane,
2-alpha,3-alpha-epithio-17-beta-(1-methoxycyclopentyl
oxy)-
- CAS REGISTRY NUMBER :
- 21362-69-6
- LAST UPDATED :
- 199209
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C25-H40-O2-S
- MOLECULAR WEIGHT :
- 404.71
- WISWESSER LINE NOTATION :
- T G5 D6 C663 RSTJ C1 G1 HO- AL5TJ AO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 400 ug/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
Skin and Appendages - dermatitis, other (after systemic exposure)
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - transaminases
- REFERENCE :
- CANCAR Cancer (Philadelphia). (Lippincott/Harper, Journal Fulfillment
Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1948-
Volume(issue)/page/year: 41,758,1978
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,779,1978
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,779,1978
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,779,1978
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >6130 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,779,1978
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >6130 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,779,1978
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >6130 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,779,1978
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 875 mg/kg/35D-C
- TOXIC EFFECTS :
- Endocrine - other changes
Blood - normocytic anemia
Nutritional and Gross Metabolic - changes in potassium
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,779,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 910 mg/kg/26W-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes in urine composition
Endocrine - changes in adrenal weight
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 16,739,1978
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 8 mg/kg
- SEX/DURATION :
- male 10 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
- REFERENCE :
- JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc.,
c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto
606, Japan) V.1- 1951- Volume(issue)/page/year: 24,551,1974
推荐供应商
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美雄烷
- 联系人：邵经理
- 电 话：16621771607
- 手 机：16621771607
- Cas号：21362-69-6
- 包装：100kg,200kg,300kg,400kg,500kg
- 纯度：
- 价格：64.0元 - 100.0元
