- 中文名称：
-
- 中文别名：
- 4-[2-hydroxy-2-(5-hydroxy-3,5-dimethyl-2-oxocyclohexyl)ethyl]piperidine-2,6-dione
- 英文名称：
- 2,6-Piperidinedione,4-[2-hydroxy-2-(5-hydroxy-3,5-dimethyl-2-oxocyclohexyl)ethyl]-
- 英文别名：
- 4-[2-hydroxy-2-(5-hydroxy-3,5-dimethyl-2-oxocyclohexyl)ethyl]piperidine-2,6-dione;
Streptovitacin A;
Resactin A;
U 9361;
Streptovitacin
- CAS No.：
- 523-86-4
- 分 子 式：
-
C15H23NO5
- 分 子 量：
- 297.39
- 精确分子量：
- 297.15800
- PSA：
- 103.70000
- InChI：
- The Key: NFDQYBUVHVRNNY-VATFKXGISA-N3
- 安全术语：
- Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MA4900000
- CHEMICAL NAME :
- Glutarimide,
3-(2-hydroxy-2-(5-hydroxy-3,5-dimethyl-2-oxocyclohexy
l)ethyl)-, (-)-
- CAS REGISTRY NUMBER :
- 523-86-4
- LAST UPDATED :
- 199109
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C15-H23-N-O5
- MOLECULAR WEIGHT :
- 297.39
- WISWESSER LINE NOTATION :
- T6VMVTJ EYQ1- BL6VTJ DQ D1 F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UPJOH* "Compounds Available for Fundamental Research, Volume II-6,
Antibiotics, A Program of Upjohn Company Research Laboratory." (Kalamazoo,
MI 49001) Volume(issue)/page/year: 2(6),-,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 920 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Gastrointestinal - hypermotility, diarrhea
Skin and Appendages - hair
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 136,400,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3952 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCISP* National Cancer Institute Screening Program Data Summary,
Developmental Therapeutics Program. (Bethesda, MD 20205)
Volume(issue)/page/year: JAN1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For
publisher information, see CTRRDO. Volume(issue)/page/year: 30,9,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 11 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UPJOH* "Compounds Available for Fundamental Research, Volume II-6,
Antibiotics, A Program of Upjohn Company Research Laboratory." (Kalamazoo,
MI 49001) Volume(issue)/page/year: 2(6),-,1971
