- 中文名称：
-
- 中文别名：
-
- 英文名称：
- 3-Buten-2-amine,N-ethyl-N-methyl-4,4-di-2-thienyl-, hydrochloride (9CI)
- 英文别名：
- Ethylmethylthiambutene Hydrochloride;
N-Ethyl-N-methyl-4,4-di(2-thienyl)-3-buten-2-aminium chloride
- CAS No.：
- 64037-50-9
- 分 子 式：
-
C15H19NS2.ClH
- 分 子 量：
- 313.93
- 精确分子量：
- 313.07300
- PSA：
- 59.72000
- InChI：
- The Key: ISXRXBARLXCMSX-UHFFFAOYSA-N3
- 安全术语：
- Poison by ingestion, intravenous, and subcutaneous routes. Used as a narcotic analgesic. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl. See also ALLYL COMPOUNDS and AMINES.
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 沸点：
- 385.7ºC at 760mmHg
- 闪点：
- 187.1ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BA6345000
- CHEMICAL NAME :
- Allylamine, N,1-dimethyl-3,3-di-2-thienyl-N-ethyl-,
hydrochloride
- CAS REGISTRY NUMBER :
- 64037-50-9
- LAST UPDATED :
- 199112
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C15-H19-N-S2.Cl-H
- MOLECULAR WEIGHT :
- 313.93
- WISWESSER LINE NOTATION :
- T5SJ BYU1Y1&N2&1&- BT5SJ &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 63 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - excitement
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 8,2,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 192 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 107,385,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 88 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 107,385,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - excitement
Behavioral - analgesia
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 8,2,1953
