- 中文名称：
-
- 中文别名：
- 1-(2-chloroethyl)-3-(4-hydroxycyclohexyl)-1-nitroso-urea
- 英文名称：
- Urea,N-(2-chloroethyl)-N'-(trans-4-hydroxycyclohexyl)-N-nitroso-
- 英文别名：
- Urea, 1-(2-chloroethyl)-3-(trans-4-hydroxycyclohexyl)-1-nitroso-;
trans-4-OH CCNU;
4-hydroxylomustine
- CAS No.：
- 56239-24-8
- 分 子 式：
-
C9H16ClN3O3
- 分 子 量：
- 249.73
- 精确分子量：
- 249.08800
- PSA：
- 82.00000
- InChI：
- The Key: BTNKSMIZKSHDNT-ZKCHVHJHSA-N3
- 安全术语：
- Poison by implant, intravenous and intraperitoneal routes. Human mutation data reported. Many N-nitroso compounds are carcinogens. When heated to decomposition it emits very toxic fumes of NOx and Cl−. See also N-NITROSO COMPOUNDS.
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 密度：
- 1.46g/cm3
- 存储条件/存储方法：
- 库房低温通风干燥,与食品原料分开存放
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YS4983500
- CHEMICAL NAME :
- Urea,
1-(2-chloroethyl)-3-(trans-4-hydroxycyclohexyl)-1-nit
roso-
- CAS REGISTRY NUMBER :
- 56239-24-8
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C9-H16-Cl-N3-O3
- MOLECULAR WEIGHT :
- 249.73
- WISWESSER LINE NOTATION :
- L6TJ AQ DMVNNO&2G -TRANS
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 52420 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD10 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 12 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intrapleural
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 35 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Human Embryo
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
44,1352,1984
