2-氨基-3,4-二甲基-3H-咪唑并喹啉
- 中文名称：
- 2-氨基-3,4-二甲基-3H-咪唑并喹啉
- 中文别名：
- 2-氨基-3,4-二甲基-3H-咪唑并喹啉;
2-氨基-3,4-二甲基-3H-咪唑并 [4,5-f]喹啉
- 英文名称：
- 3H-Imidazo[4,5-f]quinolin-2-amine,3,4-dimethyl-
- 英文别名：
- 3,4-dimethylimidazo[4,5-f]quinolin-2-amine;
Methyl IQ;
Me IQ;
3,4-dimethyl-3H-imidazoMelQ;
2-amino-3,4-dimethylimidazo<4,5-f>quinoline
- CAS No.：
- 77094-11-2
- 分 子 式：
-
C12H12N4
- 分 子 量：
- 212.28
- 精确分子量：
- 212.10600
- PSA：
- 56.73000
- InChI：
- The Key: GMGWMIJIGUYNAY-UHFFFAOYSA-N3
- 危险品标志：
- 安全术语：
- Confirmed carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
2-氨基-3,4-二甲基-3H-咪唑并喹啉 物化性质
- 密度：
- 1.36g/cm3
- 熔点：
- 291-293ºC
- 沸点：
- 465.7ºC at 760 mmHg
- 闪点：
- 235.4ºC
- 折射率：
- 1.725
- 存储条件/存储方法：
- 库房通风低温干燥
2-氨基-3,4-二甲基-3H-咪唑并喹啉 安全信息
- 海关代码：
- 2933990090
- 危险标志：
- T: Toxic;
2-氨基-3,4-二甲基-3H-咪唑并喹啉 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NJ5907000
- CHEMICAL NAME :
- 3H-Imidazo(4,5-f)quinoline, 2-amino-3,4-dimethyl-
- CAS REGISTRY NUMBER :
- 77094-11-2
- LAST UPDATED :
- 199807
- DATA ITEMS CITED :
- 30
- MOLECULAR FORMULA :
- C12-H12-N4
- MOLECULAR WEIGHT :
- 212.28
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5040 mg/kg/40W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Skin and Appendages - tumors
Endocrine - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7476 mg/kg/89W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 22120 mg/kg/81W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Gastrointestinal - tumors
Liver - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 27888 mg/kg/83W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Gastrointestinal - tumors
Liver - tumors
- TYPE OF TEST :
- Specific locus test
- TYPE OF TEST :
- Morphological transformation
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- Sister chromatid exchange
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - guinea pig Lung
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For
publisher information, see EMMUEG. Volume(issue)/page/year: 7,245,1985
*** REVIEWS ***
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 56,197,1993
IARC Cancer Review:Animal Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 40,275,1986
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 40,275,1986
IARC Cancer Review:Human Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 56,197,1993
IARC Cancer Review:Group 2B
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 56,197,1993
2-氨基-3,4-二甲基-3H-咪唑并喹啉 海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
2-氨基-3,4-二甲基-3H-咪唑并喹啉 上游产品
