地那林
- 中文名称:
- 地那林
- 中文别名:
- 地那林;
7-Amino-2(1H)-quinolinone;
7-aminoquinolin-2(1H)-one;
9,9'-[1,1'-biphenyl]-4,4'-diylbis-9H-Carbazole;
N,N'-bis(phenanthren-9-yl)-N,N'-bis(phenyl)-benzidine;
9,9'-biphenyl-4,4'-diylbis(9H-carbazole);
4,4'-Bis(9H-carbazol-9-yl)biphenyl;
CBP;
4,4'-Bis(N-carbazo-9-lyl)-1,1'-biphenyl;
4,4'-di(N-9H-carbazolyl)biphenyl;
4,4'-bis(carbazol-9-yl)biphenyl;
4,4'-Bis(9-carbazolyl)-1,1'-biphenyl;
Isepamicinum [Latin];
O-6-Amino-6-deoxy-alpha-D-glucopyranosyl-(1-4)-
- 英文名称:
- Benzamide,4-amino-N-(2-aminophenyl)-
- 英文别名:
- 4-amino-N-(2-aminophenyl)benzamide;
Goe-1734;
4-Amino-N-(2'-aminophenyl)-benzamide;
Dinaline [INN];
Dinalina [Spanish];
2',4-Diaminobenzanilide;
Dinaline [French];
2',4-Diaminobenzanilid;
Dinaline;
Dianiline;
Dinalinum [Latin]
- CAS No.:
- 58338-59-3
- 分 子 式:
-
C13H13N3O
- 分 子 量:
- 227.26
- 精确分子量:
- 227.10600
- PSA:
- 81.14000
- InChI:
- InChI=1/C13H13N3O/c14-10-7-5-9(6-8-10)13(17)16-12-4-2-1-3-11(12)15/h1-8H,14-15H2,(H,16,17)3
- 安全术语:
- Poison by ingestion. Mutation data reported. Questionable carcinogen with experimental tumorigenic data reported. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式:
-

- SDS:
- 查看
地那林 物化性质
- 密度:
- 1.314g/cm3
- 沸点:
- 367.2ºC at 760mmHg
- 闪点:
- 175.9ºC
- 折射率:
- 1.734
地那林 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CU8994000
- CHEMICAL NAME :
- Benzamide, 4-amino-N-(2-aminophenyl)-
- CAS REGISTRY NUMBER :
- 58338-59-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C13-H13-N3-O
- MOLECULAR WEIGHT :
- 227.29
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 95 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 625 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Behavioral - ataxia
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 630 mg/kg/6W-I
- TOXIC EFFECTS :
- Blood - changes in bone marrow (not otherwise specified)
Blood - changes in erythrocyte (RBC) count
Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 462 mg/kg/14W-I
- TOXIC EFFECTS :
- Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6678 mg/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria
Endocrine - adrenal cortex tumors
Reproductive - Maternal Effects - uterus, cervix, vagina
MUTATION DATA
- TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/kg
- REFERENCE :
- CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For
publisher information, see JNCIEQ. Volume(issue)/page/year: 69,1415,1985