N-[4-[[(2-氨基-3,4-二氢-4-氧代-6-蝶啶基)甲基]氨基]苯甲酰基]-L-谷氨酸钠盐(1:1)
- 中文名称：
- N-[4-[[(2-氨基-3,4-二氢-4-氧代-6-蝶啶基)甲基]氨基]苯甲酰基]-L-谷氨酸钠盐(1:1)
- 中文别名：
-
- 英文名称：
- L-Glutamic acid,N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, sodiumsalt (1:1)
- 英文别名：
- sodium folate
- CAS No.：
- 6484-89-5
- 分 子 式：
-
C19H19N7O6.Na
- 分 子 量：
- 485.36112
- 精确分子量：
- 463.12200
- PSA：
- 216.11000
- EINECS：
- 229-348-3
- 分子结构式：
-
- SDS：
- 查看
N-[4-[[(2-氨基-3,4-二氢-4-氧代-6-蝶啶基)甲基]氨基]苯甲酰基]-L-谷氨酸钠盐(1:1) 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LP5700000
- CHEMICAL NAME :
- Folic acid, monosodium salt
- CAS REGISTRY NUMBER :
- 6484-89-5
- LAST UPDATED :
- 198909
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H18-N7-O6.Na
- MOLECULAR WEIGHT :
- 463.43
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 526 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
- REFERENCE :
- ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of
Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877-
Volume(issue)/page/year: 48,289,1946
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 631 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
- REFERENCE :
- ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of
Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877-
Volume(issue)/page/year: 48,289,1946
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 431 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
- REFERENCE :
- ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of
Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877-
Volume(issue)/page/year: 48,289,1946
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 126 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
- REFERENCE :
- ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of
Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877-
Volume(issue)/page/year: 48,289,1946
