3,8-二氨基-5-乙基-6-苯基菲啶氯化物
- 中文名称：
- 3,8-二氨基-5-乙基-6-苯基菲啶氯化物
- 中文别名：
- 3,8-二氨基-5-乙基-6-苯基菲啶氯化物
- 英文名称：
- Phenanthridinium,3,8-diamino-5-ethyl-6-phenyl-, chloride (1:1)
- 英文别名：
- 5-ethyl-6-phenylphenanthridin-5-ium-3,8-diamine,chloride;
Novidium chloride;
homidium chloride;
Ethidium chloride;
Phenanthridinium,3,8-diamino-5-ethyl-6-phenyl chloride;
3,8-Diamino-5-ethyl-6-phenylphenanthridinium chloride;
Babidium chloride;
2,7-Diamino-9-phenyl-10-ethylphenanthridinium chloride;
EINECS 210-018-2;
[3H]-Ethidium
- CAS No.：
- 602-52-8
- 分 子 式：
-
C21H20N3.Cl
- 分 子 量：
- 349.89
- 精确分子量：
- 349.13500
- PSA：
- 55.92000
- EINECS：
- 210-018-2
- InChI：
- The Key: BITVSRNAFFZUFW-UHFFFAOYSA-N3
- 安全术语：
- Poison by subcutaneous and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx and Cl−.
- 分子结构式：
-
- SDS：
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3,8-二氨基-5-乙基-6-苯基菲啶氯化物 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SF7960000
- CHEMICAL NAME :
- Phenanthridinium, 3,8-diamino-5-ethyl-6-phenyl-,
chloride
- CAS REGISTRY NUMBER :
- 602-52-8
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C21-H20-N3.Cl
- MOLECULAR WEIGHT :
- 349.89
- WISWESSER LINE NOTATION :
- T B666 HKJ EZ H2 IR& LZ &Q &G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 21 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- NCINS* National Cancer Institute Report. (Bethesda, MD 20014)
Volume(issue)/page/year: -,107,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCINS* National Cancer Institute Report. (Bethesda, MD 20014)
Volume(issue)/page/year: -,107,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56370 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCISP* National Cancer Institute Screening Program Data Summary,
Developmental Therapeutics Program. (Bethesda, MD 20205)
Volume(issue)/page/year: JAN1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 14 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- NCINS* National Cancer Institute Report. (Bethesda, MD 20014)
Volume(issue)/page/year: -,107,1965
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 17640 ug/kg/28D-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - chronic pulmonary edema
Skin and Appendages - dermatitis, other (after systemic exposure)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- NCINS* National Cancer Institute Report. (Bethesda, MD 20014)
Volume(issue)/page/year: -,107,1965
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 17640 ug/kg/28D-I
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea
Skin and Appendages - dermatitis, other (after systemic exposure)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- NCINS* National Cancer Institute Report. (Bethesda, MD 20014)
Volume(issue)/page/year: -,107,1965
3,8-二氨基-5-乙基-6-苯基菲啶氯化物 下游产品
