羧基邻苯二甲酸-1,2-二氨基环己烷铂
- 中文名称：
- 羧基邻苯二甲酸-1,2-二氨基环己烷铂
- 中文别名：
-
- 英文名称：
- Platinate(1-),[1,2,4-benzenetricarboxylato(3-)-kO1,kO2][(1R,2R)-1,2-cyclohexanediamine-kN,kN']-, hydrogen, (SP-4-3)- (9CI)
- 英文别名：
- Platinate(1-), [1,2,4-benzenetricarboxylato(3-)-O1,O2](1,2-cyclohexanediamine-N,N')-, hydrogen, (SP-4-3)-;
carboxyphthalato-1,2-diaminocyclohexaneplatinum
- CAS No.：
- 65296-81-3
- 分 子 式：
-
C15H17N2O6Pt.H
- 分 子 量：
- 517.44
- 精确分子量：
- 515.06600
- PSA：
- 113.96000
- InChI：
- The Key: WQEBMDXDYKHCSG-UHFFFAOYSA-L3
- 安全术语：
- Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. See also PLATINUM COMPOUNDS.
- 分子结构式：
-
- SDS：
- 查看
羧基邻苯二甲酸-1,2-二氨基环己烷铂 物化性质
- 沸点：
- 505.5ºC at 760 mmHg
羧基邻苯二甲酸-1,2-二氨基环己烷铂 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TP1385500
- CHEMICAL NAME :
- Platinate (1-),
(1,2,4-benzenetricarboxylato(3-)-O(sup 1),O(sup
2))(1,2-cyclohexanediamine- N,N')-, hydrogen,
(SP-4-3)-
- CAS REGISTRY NUMBER :
- 65296-81-3
- LAST UPDATED :
- 199509
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C15-H18-N2-O6-Pt
- MOLECULAR WEIGHT :
- 517.44
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 84 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified
Gastrointestinal - hypermotility, diarrhea
Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46100 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 40130 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 70 mg/kg/5D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Blood - changes in bone marrow (not otherwise specified)
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - phosphatases
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 33 umol/L
- REFERENCE :
- NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4-
1957- Volume(issue)/page/year: 34,379,1987
