异舒普林
- 中文名称：
- 异舒普林
- 中文别名：
- 异舒普林
- 英文名称：
- Benzenemethanol,4-hydroxy-a-[1-[(1-methyl-2-phenoxyethyl)amino]ethyl]-
- 英文别名：
- 4-[1-hydroxy-2-(1-phenoxypropan-2-ylamino)propyl]phenol;
EINECS 206-898-2;
Isoxsuprina [INN-Spanish];
Dilavase;
1-(p-hydroxyphenyl)-2-(1'-methyl-2'-phenoxyethylamino)-1-propanol;
isoxsuprine;
Isoxsuprine [INN:BAN];
1-(4-hydroxyphenyl)-2-(1-methyl-2-phenoxyethylamino)-1-propanol;
isoxspurine;
Isoxsuprinum [INN-Latin];
Vasodilian;
Vasosurpine
- CAS No.：
- 395-28-8
- 分 子 式：
-
C18H23NO3
- 分 子 量：
- 301.42
- 精确分子量：
- 301.16800
- PSA：
- 61.72000
- InChI：
- The Key: BMUKKTUHUDJSNZ-PMUMKWKESA-N3
- 安全术语：
- Poison by ingestion, intravenous and intraperitoneal routes. A human teratogen. Human reproductive effects by ingestion: uterus, cervix and vagina effects. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. Used to delay premature parturition (labor) and to accelerate fetal lung development.
- 分子结构式：
-
- SDS：
- 查看
异舒普林 物化性质
- 密度：
- 1.146g/cm3
- 沸点：
- 484.2ºC at 760mmHg
- 闪点：
- 246.6ºC
异舒普林 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DO8050000
- CHEMICAL NAME :
- Benzyl alcohol,
p-hydroxy-alpha-(1-((1-methyl-2-phenoxyethyl)amino)et
hyl)-
- CAS REGISTRY NUMBER :
- 395-28-8
- LAST UPDATED :
- 199601
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C18-H23-N-O3
- MOLECULAR WEIGHT :
- 301.42
- WISWESSER LINE NOTATION :
- QR DYQY1&MY1&1OR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex)
Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 21,1992,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 118 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
Italy) V.8-43 1953-88 For publisher information, see FRMCE8
Volume(issue)/page/year: 38,571,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 48 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
(Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
V.9- 1974- Volume(issue)/page/year: 10,291,1975
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 800 ug/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
- REFERENCE :
- RDCNBM Reproduccion. (Madrid, Spain) V.1-7, 1974-83. Discontinued.
Volume(issue)/page/year: 5,31,1981
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 350 ug/kg
- SEX/DURATION :
- female 26 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - cardiovascular
(circulatory) system
Reproductive - Specific Developmental Abnormalities - gastrointestinal
system
Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
per # born alive)
- REFERENCE :
- JOPDAB Journal of Pediatrics. (C.V. Mosby Co., 11830 Westline Industrial
Dr., St. Louis, MO 63141) V.1- 1932- Volume(issue)/page/year:
94,444,1979
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 350 ug/kg
- SEX/DURATION :
- female 32 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - blood and lymphatic
systems (including spleen and marrow)
- REFERENCE :
- JOPDAB Journal of Pediatrics. (C.V. Mosby Co., 11830 Westline Industrial
Dr., St. Louis, MO 63141) V.1- 1932- Volume(issue)/page/year:
94,444,1979
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 10 mg/kg
- SEX/DURATION :
- female 25 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - other effects to embryo
Reproductive - Specific Developmental Abnormalities - respiratory system
- REFERENCE :
- PEREBL Pediatric Research. (Williams & Wilkins Co., 428 E. Preston St.,
Baltimore, MD 21202) V.1- 1967- Volume(issue)/page/year: 14,278,1980
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 10 mg/kg
- SEX/DURATION :
- female 26 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - biochemical and metabolic
- REFERENCE :
- AJOGAH American Journal of Obstetrics and Gynecology. (C.V. Mosby Co.,
11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1920-
Volume(issue)/page/year: 129,691,1977
推荐供应商
湖北恩星生物科技有限公司
异舒普林
- 联系人：邵经理
- 电 话：16621771607
- 手 机：16621771607
- Cas号：395-28-8
- 包装：100kg,200kg,300kg,400kg,500kg
- 纯度：
- 价格：64.0元 - 100.0元
