夾可鹼
- 中文名称：
- 夾可鹼
- 中文别名：
- 夾可鹼
- 英文名称：
- Spiro[[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-3(2H),2'-oxirane]-2,7(4H)-dione,5,6,9,11,13,14,14a,14b-octahydro-6-hydroxy-3',5,6-trimethyl-,(2'S,3'S,5R,6R,14aR,14bR)-
- 英文别名：
- Jacobine;
(15R,20S)-15,20-Dihydro-15,20-epoxy-12-hydroxysenecionan-11,16-dione
- CAS No.：
- 6870-67-3
- 分 子 式：
-
C18H25NO6
- 分 子 量：
- 351.44
- 精确分子量：
- 351.16800
- PSA：
- 88.60000
- InChI：
- The Key: IAPHXJRHXBQDQJ-WKMWQDDRSA-N3
- 安全术语：
- Poison by intravenous route. Questionable carcinogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
夾可鹼 物化性质
- 密度：
- 1.33g/cm3
- 熔点：
- 228ºC
- 沸点：
- 574.1ºC at 760 mmHg
- 闪点：
- 301ºC
- 折射率：
- 1.583
夾可鹼 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NY5775000
- CHEMICAL NAME :
- Jacobine
- CAS REGISTRY NUMBER :
- 6870-67-3
- BEILSTEIN REFERENCE NO. :
- 0054580
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C18-H25-N-O6
- MOLECULAR WEIGHT :
- 351.44
- WISWESSER LINE NOTATION :
- T55-12- 1A Q EN IOVX OVO BUTJ M1 NQ N1 K-& BT3OX CHJ
C1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 77 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory stimulation
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- DNA damage
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - rat Liver
- DOSE/DURATION :
- 1 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
45,3125,1985
*** REVIEWS ***
IARC Cancer Review:Animal Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 10,275,1976
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 10,275,1976
IARC Cancer Review:Group 3
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,56,1987
TOXICOLOGY REVIEW
CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For
publisher information, see JNCIEQ. Volume(issue)/page/year: 60,1171,1976
推荐供应商
湖北恩星生物科技有限公司
夾可鹼
- 联系人：邵经理
- 电 话：16621771607
- 手 机：16621771607
- Cas号：6870-67-3
- 包装：100kg,200kg,300kg,400kg,500kg
- 纯度：
- 价格：64.0元 - 100.0元
