他利霉素
- 中文名称：
- 他利霉素
- 中文别名：
- 他利霉素;
泰来霉素 太利苏霉素
- 英文名称：
- Bleomycinamide,N1-[4-amino-6-[[3-[(4-aminobutyl)amino]propyl]amino]-6-oxohexyl]-13-[(4-amino-4,6-dideoxy-a-L-talopyranosyl)oxy]-19-demethyl-12-hydroxy-
- 英文别名：
- Talisomycin;
Antibiotic BU-2231A;
Tallysomycin A;
Bu-2231A
- CAS No.：
- 65057-90-1
- 分 子 式：
-
C68H110N22O27S2
- 分 子 量：
- 1732.12
- 精确分子量：
- 1730.74000
- PSA：
- 881.89000
- 安全术语：
- Poison by intraperitoneal, subcutaneous and intravenous routes. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx.
- 分子结构式：
-
- SDS：
- 查看
他利霉素 物化性质
- 密度：
- 1.58g/cm3
- 折射率：
- 1.686
他利霉素 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EC5990300
- CHEMICAL NAME :
- Bleomycinamide, N(sup
1)-(4-amino-6-((3-((4-aminobutyl)amino)propyl)amino)-
6-oxohexyl)-
13-((4-amino-4,6-dideoxy-alpha-L-talopyranosyl)oxy)-1
9-demethyl-12-hydroxy-
- CAS REGISTRY NUMBER :
- 65057-90-1
- LAST UPDATED :
- 199512
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C68-H110-N22-O27-S2
- MOLECULAR WEIGHT :
- 1732.12
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 19 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 28 mg/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 40 mg/kg/4W-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - fibrosis (interstitial)
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 100 ug/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 113,288,1983
推荐供应商
浙江珲达生物科技有限公司
他利霉素
- 联系人：珲达
- 电 话：13515763466
- 手 机：19931153253
- Cas号：65057-90-1
- 包装：asperrequest
- 纯度：95%
- 价格：洽谈
