睇波芬
- 中文名称：
- 睇波芬
- 中文别名：
-
- 英文名称：
- Antimonate(5-),bis[4,5-di(hydroxy-kO)-1,3-benzenedisulfonato(4-)]-, sodium, hydrate (1:5:7), (T-4)-
- 英文别名：
- pentasodium,2-(2-oxido-3,5-disulfonatophenoxy)-1,3,2-benzodioxastibole-4,6-disulfonate,heptahydrate;
Stibophenum;
Sodium antimosan;
Stibophen-7-wasser;
Fantorin;
Pyrostib;
Fuadin;
Neoantimosan;
Corystibin;
Stibofen;
Trimon
- CAS No.：
- 15489-16-4
- 分 子 式：
-
C12H4O16S4Sb.7H2O.5Na
- 分 子 量：
- 799.24
- 精确分子量：
- 767.69100
- PSA：
- 313.07000
- 安全术语：
- Poison by intraperitoneal, intramuscular, and intravenous routes. Moderately toxic by intraperitoneal route. See also ANTIMONY COMPOUNDS and SULFONATES. When heated to decomposition it emits toxic fumes of Sb and Na2O.
- 分子结构式：
-
- SDS：
- 查看
睇波芬 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CC2850000
- CHEMICAL NAME :
- Antimonate (5-),
bis(4,5-dihydroxy-m-benzenedisulfonato(4-))-,
pentasodium, heptahydrate
- CAS REGISTRY NUMBER :
- 15489-16-4
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 32
- MOLECULAR FORMULA :
- C12-H4-O16-S4-Sb.7H2-O.5Na
- MOLECULAR WEIGHT :
- 799.24
- WISWESSER LINE NOTATION :
- QSQO&R BQ CQ ESQO&O-SB-QOSQO&R CQ DQ ESQQO &QH 7
&-NA- 5
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
Volume(issue)/page/year: 90,122,1955
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 260 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AJTMAQ American Journal of Tropical Medicine. (Baltimore, MD) V.1-31,
1921-51. For publisher information, see AJTHAB. Volume(issue)/page/year:
25,263,1945
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 670 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BWHOA6 Bulletin of the World Health Organization. (WHO, Pub. Center USA, 49
Sheridan Ave., Albany, NY 12210) Volume(issue)/page/year: 45,371,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1050 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research.
(Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way,
Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 17,108,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 90 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 89,196,1947
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 91 mg/kg
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 87,119,1946
*** REVIEWS ***
ACGIH TLV-TWA 0.5 mg(Sb)/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
*** U.S. STANDARDS AND REGULATIONS ***
MSHA STANDARD-air:TWA 0.5 mg(Sb)/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,15,1971
OSHA PEL (Gen Indu):8H TWA 0.5 mg(Sb)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 0.5 mg(Sb)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 0.5 mg(Sb)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 0.5 mg(Sb)/m3
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-ARAB Republic of Egypt:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL-AUSTRALIA:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL-AUSTRIA:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL-BELGIUM:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL-DENMARK:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL-FINLAND:.TWA (0.5 mg(Sb)/m3) JAN 1993
OEL-FRANCE:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL-GERMANY:TWA 0.5 mg(Sb)/m3 (total dust) JAN 1993
OEL-HUNGARY:STEL 0.5 mg(Sb)/m3 JAN 1993
OEL-THE NETHERLANDS:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL-THE PHILIPPINES:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL-POLAND:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL-RUSSIA:TWA 0.2 mg(Sb)/m3;STEL 0.5 mg(Sb)/m3 JAN 1993
OEL-SWEDEN:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL-SWITZERLAND:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL-TURKEY:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 0.5 mg(Sb)/m3 JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO ANTIMONY-air:10H TWA 0.5 mg(Sb)/m3
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
