3-(3-甲基磺酰基氧基丙基氨基)丙基甲烷磺酸酯盐酸盐
- 中文名称：
- 3-(3-甲基磺酰基氧基丙基氨基)丙基甲烷磺酸酯盐酸盐
- 中文别名：
-
- 英文名称：
- 1-Propanol,3,3'-iminobis-, 1,3-dimethanesulfonate, hydrochloride (1:1)
- 英文别名：
- 1-Propanol,3,3'-iminobis-, 1,3-dimethanesulfonate, hydrochloride (1:1)
- CAS No.：
- 3458-22-8
- 分 子 式：
-
C8H19NO6S2.ClH
- 分 子 量：
- 325.86
- 精确分子量：
- 325.04200
- PSA：
- 115.53000
- 安全术语：
- Poison by intraperitoneal and intravenous routes. Human systemic effects by intravenous route: somnolence, hypermotility, diarrhea, nausea or vomiting. Questionable carcinogen with experimental neoplastigenic data. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl.
- 分子结构式：
-
- SDS：
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3-(3-甲基磺酰基氧基丙基氨基)丙基甲烷磺酸酯盐酸盐 物化性质
- 熔点：
- 94-95ºC
- 沸点：
- 510.1ºC at 760mmHg
- 闪点：
- 262.3ºC
3-(3-甲基磺酰基氧基丙基氨基)丙基甲烷磺酸酯盐酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UB6620000
- CHEMICAL NAME :
- 1-Propanol, 3,3'-iminodi-, dimethanesulfonate
(ester), hydrochloride
- CAS REGISTRY NUMBER :
- 3458-22-8
- LAST UPDATED :
- 199506
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C8-H19-N-O6-S2.Cl-H
- MOLECULAR WEIGHT :
- 325.86
- WISWESSER LINE NOTATION :
- WS1&O3M3OSW1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 5400 ug/kg/2D-I
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Gastrointestinal - hypermotility, diarrhea
Gastrointestinal - nausea or vomiting
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD10 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 170 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 432 mg/kg/6W-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1440 mg/kg/6W-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3744 mg/kg/52W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria
Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1100 mg/kg/8W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3840 mg/kg/64W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria
Tumorigenic - tumors at site of application
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 100 mg/L
- REFERENCE :
- EJCAAH European Journal of Cancer. (Oxford, UK) V.1-17(6), 1965-1981. For
publisher information, see EJCODS. Volume(issue)/page/year: 14,741,1978
