左沙屈尔
- 中文名称：
- 左沙屈尔
- 中文别名：
- 左沙屈尔;
异二苯氧茂哌啶
- 英文名称：
- Piperidine,2-[(4R)-2,2-diphenyl-1,3-dioxolan-4-yl]-, hydrochloride (1:1), (2R)-
- 英文别名：
- Piperidine, (+)-2-(2,2-diphenyl-1,3-dioxolan-4-yl)-, hydrochloride;
Levoxadrol;
Levoxan;
Cl-912c
- CAS No.：
- 23257-58-1
- 分 子 式：
-
C20H23NO2.ClH
- 分 子 量：
- 345.90
- 精确分子量：
- 345.15000
- PSA：
- 30.49000
- 安全术语：
- Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx and HCl.
- 分子结构式：
-
- SDS：
- 查看
左沙屈尔 物化性质
- 沸点：
- 468.4ºC at 760mmHg
- 闪点：
- 237.1ºC
- 蒸汽压：
- 3.6E-09mmHg at 25°C
左沙屈尔 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TM7640000
- CHEMICAL NAME :
- Piperidine, 2-(2,2-diphenyl-1,3-dioxolan-4-yl)-,
hydrochloride, l-
- CAS REGISTRY NUMBER :
- 23257-58-1
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H23-N-O2.Cl-H
- MOLECULAR WEIGHT :
- 345.90
- WISWESSER LINE NOTATION :
- T6MTJ B- DT5O COTJ BR& BR &GH -L
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 310 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 153,105,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex)
Behavioral - ataxia
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 153,105,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Behavioral - anticonvulsant
Behavioral - altered sleep time (including change in righting reflex)
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 153,105,1965
