(16S,17R)-3-甲氧基-13,16-二甲基-7,8,9,11,12,14,15,17-八氢-6H-环戊二烯并[a]菲-16,17-二醇
- 中文名称：
- (16S,17R)-3-甲氧基-13,16-二甲基-7,8,9,11,12,14,15,17-八氢-6H-环戊二烯并[a]菲-16,17-二醇
- 中文别名：
-
- 英文名称：
- Estra-1,3,5(10)-triene-16,17-diol,3-methoxy-16-methyl-, (16b,17b)-
- 英文别名：
- mytatrienediol;
Manvene;
Mytatrienediol;
17.β.-Estradiol, 16.β.-hydroxy-16-methyl-, 3-methyl ether;
16b-Hydroxy-16-methyl-3-methyl ether 17b-estradiol
- CAS No.：
- 5108-94-1
- 分 子 式：
-
C20H28O3
- 分 子 量：
- 0
- 精确分子量：
- 316.20400
- PSA：
- 49.69000
- InChI：
- The Key: OOVXZFCPCSVSEM-HPYOWSOTSA-N3
- 分子结构式：
-
- SDS：
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(16S,17R)-3-甲氧基-13,16-二甲基-7,8,9,11,12,14,15,17-八氢-6H-环戊二烯并[a]菲-16,17-二醇 物化性质
- 密度：
- 1.156g/cm3
- 沸点：
- 451.3ºC at 760mmHg
- 闪点：
- 226.8ºC
- 折射率：
- 1.575
(16S,17R)-3-甲氧基-13,16-二甲基-7,8,9,11,12,14,15,17-八氢-6H-环戊二烯并[a]菲-16,17-二醇 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KG7550000
- CHEMICAL NAME :
- Estra-1,3,5(10)-triene-16-beta,17-beta-diol,
3-methoxy-16-methyl-
- CAS REGISTRY NUMBER :
- 5108-94-1
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H28-O3
- MOLECULAR WEIGHT :
- 316.48
- WISWESSER LINE NOTATION :
- L E5 B666TTT&J E1 FQ GQ G1 OO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 35 mg/kg
- SEX/DURATION :
- female 35 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant
per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston
St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year:
63,561,1958
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- DOSE :
- 30 mg/kg
- SEX/DURATION :
- female 30 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
- REFERENCE :
- RPHRA6 Recent Progress In Hormone Research. Proceedings of the Laurentian
Hormone Conference. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1947- Volume(issue)/page/year: 20,395,1964
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 12 mg/kg
- SEX/DURATION :
- female 4-6 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant
per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot,
POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960-
Volume(issue)/page/year: 9,277,1965
