4'-[二(2-氯乙基)氨基]-2-氟乙酰苯胺
- 中文名称：
- 4'-[二(2-氯乙基)氨基]-2-氟乙酰苯胺
- 中文别名：
-
- 英文名称：
- Acetamide,N-[4-[bis(2-chloroethyl)amino]phenyl]-2-fluoro-
- 英文别名：
- N-[4-[bis(2-chloroethyl)amino]phenyl]-2-fluoroacetamide;
p-Fluoroacetylaminophenyl derivative of nitrogen mustard
- CAS No.：
- 1492-93-9
- 分 子 式：
-
C12H15Cl2FN2O
- 分 子 量：
- 293.19
- 精确分子量：
- 292.05500
- PSA：
- 32.34000
- InChI：
- The Key: HTONHMWVXDSAHU-UHFFFAOYSA-N3
- 安全术语：
- Poison by intraperitoneal route. An experimental teratogen. When heated to decomposition it emits very toxic fumes of Cl−, F−, and NOx.
- 分子结构式：
-
- SDS：
- 查看
4'-[二(2-氯乙基)氨基]-2-氟乙酰苯胺 物化性质
- 密度：
- 1.322g/cm3
- 沸点：
- 477.9ºC at 760 mmHg
- 闪点：
- 242.8ºC
- 折射率：
- 1.581
- 蒸汽压：
- 2.69E-09mmHg at 25°C
- 存储条件/存储方法：
- 库房通风低温干燥,与食品原料分开存放
4'-[二(2-氯乙基)氨基]-2-氟乙酰苯胺 安全信息
4'-[二(2-氯乙基)氨基]-2-氟乙酰苯胺 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AD9310000
- CHEMICAL NAME :
- Acetanilide, 4'-(bis(2-chloroethyl)amino)-2-fluoro-
- CAS REGISTRY NUMBER :
- 1492-93-9
- BEILSTEIN REFERENCE NO. :
- 2815229
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C12-H15-Cl2-F-N2-O
- MOLECULAR WEIGHT :
- 293.19
- WISWESSER LINE NOTATION :
- G2N2GR DMV1F
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7916 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 8,167,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 34 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 8,167,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JEEMAF Journal of Embryology and Experimental Morphology. (Essex, UK)
V.1-98, 1953-86. For Publisher information, see DEVPED
Volume(issue)/page/year: 9,492,1961
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 45 mg/kg
- SEX/DURATION :
- female 7-9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - eye/ear
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
Reproductive - Specific Developmental Abnormalities - hepatobiliary system
- REFERENCE :
- JEEMAF Journal of Embryology and Experimental Morphology. (Essex, UK)
V.1-98, 1953-86. For Publisher information, see DEVPED
Volume(issue)/page/year: 9,492,1961
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 45 mg/kg
- SEX/DURATION :
- female 7-9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- JEEMAF Journal of Embryology and Experimental Morphology. (Essex, UK)
V.1-98, 1953-86. For Publisher information, see DEVPED
Volume(issue)/page/year: 9,492,1961
4'-[二(2-氯乙基)氨基]-2-氟乙酰苯胺 海关数据
中国海关编码：2924299090
- 概述：
- 2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途, 包装
- 摘要/Summary：
- 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
