槟榔碱,63-75-2，生产厂家，价格-洛克化工网移动版

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槟榔碱

中文名称：: 槟榔碱

中文别名：: 槟榔碱;
1162 F;
4-Aminobenzenesulfonamide;
gerison;
gombardol;
Lusil;
lysococcine;
neococcyl;
orgaseptine;
Prontalbin;
prontosil albom;
Prontosil album;
prontosil i;
prontosil white;
Prontylin;
pronzin album;
proseptal;
proseptine;
proseptol;
pysococcine;
rubiazol a;
sanamid;
septamide album;
septanilam;
septinal;
septolix;
septoplex;
Septoplix;
stopton album;
stramid;
strepamide;
strepsa

英文名称：: 3-Pyridinecarboxylicacid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester

英文别名：: arecoline;
methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate;
Arekolin;
Arecolin;
Arecholine;
methyl N-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate;
methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate;
3-Methoxycarbonyl-1-methyl-1,2,5,6-tetrahydropyridine;
Arecaline;
Methylarecaiden;
methyl 1,2,5,6-tetrahydro-1-methylnicotinate;
Methylarecaidin;
Arecoline base;
Arecaidine methyl ester

CAS No.：: 63-75-2

分子式：: C₈H₁₃NO₂

分子量：: 155.22

精确分子量：: 155.09500

PSA：: 29.54000

EINECS：: 200-565-5

InChI：: The Key: HJJPJSXJAXAIPN-UHFFFAOYSA-N3

危险品标志：

风险术语：

安全术语：: Poison by subcutaneous and intraperitoneal routes. Moderately toxic by ingestion. Questionable carcinogen with experimental neoplastigenic data. It mimics the action of acetylcholine, a neuro-transmitter, and is a parasympathetic nervous system stimulant. Its action on the central nervous system can cause tremors. Human mutation data reported. It is easily nitrosated to several nitrosamines. See also

SDS：

槟榔碱毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QT2100000

CHEMICAL NAME :: Nicotinic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester

CAS REGISTRY NUMBER :: 63-75-2

BEILSTEIN REFERENCE NO. :: 0123045

LAST UPDATED :: 199703

DATA ITEMS CITED :: 21

MOLECULAR FORMULA :: C8-H13-N-O2

MOLECULAR WEIGHT :: 155.22

WISWESSER LINE NOTATION :: T6N CUTJ A1 CVO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Vascular - contraction (isolated tissues)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 550 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 190 mg/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 36 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 2698 mg/kg/65W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Unscheduled DNA synthesis

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Sister chromatid exchange

TYPE OF TEST :: Sperm Morphology

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 5 mg/L

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 5,501,1984 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 37,141,1985

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