海关代码：

29224910

WGK_Germany：

2
德国有关水污染物质的分类清单

危险类别码：

R33

安全说明：

S22-S24/25

RTECS号：

MB7600000

安全标志：

S22:不要吸入粉尘。
S24/25:防止皮肤和眼睛接触。

CHEMICAL IDENTIFICATION

RTECS NUMBER :

MB7600000

CHEMICAL NAME :

Glycine

CAS REGISTRY NUMBER :

56-40-6

LAST UPDATED :

199710

DATA ITEMS CITED :

16

MOLECULAR FORMULA :

C2-H5-N-O2

MOLECULAR WEIGHT :

75.08

WISWESSER LINE NOTATION :

Z1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

7930 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

5200 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2600 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

4920 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

4450 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

5060 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2370 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Mammal - cat

DOSE/DURATION :

3 gm/kg

TOXIC EFFECTS :

Behavioral - food intake (animal) Behavioral - muscle weakness Behavioral - ataxia

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

45 gm/kg/30D-I

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - respiratory depression Endocrine - changes in spleen weight Blood - changes in leukocyte (WBC) count

MUTATION DATA

TYPE OF TEST :

Sister chromatid exchange

TEST SYSTEM :

Human Lymphocyte

DOSE/DURATION :

100 mg/L

REFERENCE :

MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 280,279,1992 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80389 No. of Facilities: 1797 (estimated) No. of Industries: 17 No. of Occupations: 25 No. of Employees: 25710 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80389 No. of Facilities: 3706 (estimated) No. of Industries: 24 No. of Occupations: 48 No. of Employees: 115042 (estimated) No. of Female Employees: 83784 (estimated)

毒理学数据：

1、急性毒性：大鼠经口LD50：7930mg/kg；大鼠皮下LD50：5200mg/kg；

分子结构数据

1、   摩尔折射率：16.41

2、   摩尔体积（cm³/mol）59.8

3、   等张比容（90.2K）：162.5

4、   表面张力（dyne/cm）：54.4

5、   极化率（10^-24cm³）：6.50

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:2

3.氢键受体数量:3

4.可旋转化学键数量:1

5.互变异构体数量:无

6.拓扑分子极性表面积63.3

7.重原子数量:5

8.表面电荷:0

9.复杂度:42.9

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

• 
  甘氨酸红外图谱(IR1)
• 
  甘氨酸红外图谱(IR2)
• 
  甘氨酸质谱(MS)
• 
  甘氨酸Raman光谱
• 
  甘氨酸核磁图(¹HNMR)