制备方法

增塑剂，主要用于各种聚酰胺如尼龙6，66，11等以增强其可塑性、延展性并降低玻璃化温度。

用途简介

海关代码：

2935009090

WGK_Germany：

2
德国有关水污染物质的分类清单

危险类别码：

R36/37/38

安全说明：

S26-S36

RTECS号：

DB1283000

安全标志：

S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
S36:穿戴合适的防护服装。

危险标志：

Xi:Irritant;

CHEMICAL IDENTIFICATION

RTECS NUMBER :

DB1283000

CHEMICAL NAME :

Benzenesulfonamide, N-butyl-

CAS REGISTRY NUMBER :

3622-84-2

BEILSTEIN REFERENCE NO. :

2725965

LAST UPDATED :

199712

DATA ITEMS CITED :

9

MOLECULAR FORMULA :

C10-H15-N-O2-S

MOLECULAR WEIGHT :

213.32

WISWESSER LINE NOTATION :

WSR&M4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2050 mg/kg

TOXIC EFFECTS :

Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity

REFERENCE :

TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 15,110,1979

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2500 mg/kg

TOXIC EFFECTS :

Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity

REFERENCE :

TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 15,110,1979

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - species unspecified

DOSE/DURATION :

2900 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(4),86,1974 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1500 ug/m3/17W-I

TOXIC EFFECTS :

Blood - changes in other cell count (unspecified)

REFERENCE :

TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 15,110,1979

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

1500 ug/m3/17W-I

TOXIC EFFECTS :

Blood - changes in other cell count (unspecified)

REFERENCE :

TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 15,110,1979 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1683 No. of Facilities: 24 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1534 (estimated) No. of Female Employees: 1168 (estimated)

毒理学数据：

1、急性毒性：

大鼠口经LD50： 2050 mg/kg

小鼠口经LD50： 2500 mg/kg

哺乳动物口经LD50： 2900 mg/kg

2、其他多剂量毒性数据：

大鼠吸入TCLo：1500 ug/m3/17W-I

豚鼠吸入TCLo：1500 ug/m3/17W-I

生态数据：

该物质对环境可能有危害，对水体应给予特别注意

中国海关编码：2935009090

概述：

2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%

申报要素：

品名, 成分含量, 用途

摘要/Summary：

2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

分子结构数据

1、   摩尔折射率：57.74

2、   摩尔体积（m³/mol）：189.5

3、   等张比容（90.2K）：471.8

4、   表面张力（dyne/cm）：38.3

5、   极化率（10^-24cm³）：22.89

计算化学数据

1.疏水参数计算参考值（XlogP）:2.1

2.氢键供体数量:1

3.氢键受体数量:3

4.可旋转化学键数量:5

5.互变异构体数量:无

6.拓扑分子极性表面积54.6

7.重原子数量:14

8.表面电荷:0

9.复杂度:237

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

• 
  N-丁基苯磺酰胺红外图谱(IR1)
• 
  N-丁基苯磺酰胺质谱(MS)
• 
  N-丁基苯磺酰胺核磁图(¹³CNMR)
• 
  N-丁基苯磺酰胺核磁图(¹HNMR)