盐酸甲氧氮芥
- 中文名称：
- 盐酸甲氧氮芥
- 中文别名：
- 盐酸甲氧氮芥
- 英文名称：
- Ethanamine,2-chloro-N-(2-chloroethyl)-N-methyl-, N-oxide, hydrochloride (1:1)
- 英文别名：
- 2-chloro-N-(2-chloroethyl)-N-methylethanamine oxide,hydrochloride;
Mitomen;
Bis-(2-chlor-aethyl)-hydroxy-methyl-ammonium-chlorid;
Oxyamine;
N,N-Bis-(2-chlor-aethyl)-N-methyl-hydroxylaminium-chlorid;
MBAO hydrochloride;
Bis-(2-chlor-aethyl)-methyl-aminoxid,Hydrochlorid;
Mustron;
N-Oxyd-Lost;
mechlorethamine oxide hydrochloride;
Nitromin;
Ossichlorin;
Ossiamina;
Nitromin hydrochloride;
bis-(2-chloro-ethyl)-methyl-amine oxide,hydrochloride;
HN2 oxide hydrochloride
- CAS No.：
- 302-70-5
- 分 子 式：
-
C5H11Cl2NO.ClH
- 分 子 量：
- 208.53
- 精确分子量：
- 206.99800
- PSA：
- 29.43000
- InChI：
- The Key: SYNHCENRCUAUNM-UHFFFAOYSA-N3
- 安全术语：
- Suspected carcinogen with experimental tumorigenic data. Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Mutation data reported. An antineoplastic agent. When heated to decomposition it emits toxic fumes of Cl− and NOx.
- 分子结构式：
-
- SDS：
- 查看
盐酸甲氧氮芥 安全信息
- 包装等级：
- II
- 风险类别：
- 6.1(a)
- 海关代码：
- 2921199090
盐酸甲氧氮芥 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- IA2275000
- CHEMICAL NAME :
- Diethylamine, 2,2'-dichloro-N-methyl-, N-oxide,
hydrochloride
- CAS REGISTRY NUMBER :
- 302-70-5
- LAST UPDATED :
- 199510
- DATA ITEMS CITED :
- 19
- MOLECULAR FORMULA :
- C5-H11-Cl2-N-O.Cl-H
- MOLECULAR WEIGHT :
- 208.53
- WISWESSER LINE NOTATION :
- G2KO&1&2G &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 79500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 76100 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 83 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 4 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - other changes
Blood - leukopenia
Blood - other changes
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 8 mg/kg
- TOXIC EFFECTS :
- Blood - leukopenia
Blood - other changes
Blood - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Multiple routes
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1300 mg/kg/93W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
Blood - leukemia
- TYPE OF TEST :
- Cytogenetic analysis
MUTATION DATA
- TYPE OF TEST :
- Body fluid assay
- TEST SYSTEM :
- Rodent - rat Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 250 mg/kg
- REFERENCE :
- URLRA5 Urological Research. (Springer Verlag New York, Inc., Service
Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1973-
Volume(issue)/page/year: 7,119,1979
*** REVIEWS ***
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 9,209,1975
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 9,209,1975
IARC Cancer Review:Group 2B
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,56,1987
盐酸甲氧氮芥 海关数据
中国海关编码：2921199090
- 概述：
- 2921199090 其他无环单胺及其衍生物及其盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
