盐(8CI,9CI)砷酸(H3酶并4),铅
- 中文名称：
- 盐(8CI,9CI)砷酸(H3酶并4),铅
- 中文别名：
- 盐(8CI,9CI)砷酸(H3酶并4),铅
- 英文名称：
- Fluoranthene,3,7-dinitro-
- 英文别名：
- 3,7-Dinitrofluoranthene;
3,7-Dinitro-fluoranthene;
Fluoranthene,3,7-dinitro
- CAS No.：
- 105735-71-5
- 分 子 式：
-
C16H8N2O4
- 分 子 量：
- 292.26
- 精确分子量：
- 292.04800
- PSA：
- 91.64000
- 安全术语：
- Questionable carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
盐(8CI,9CI)砷酸(H3酶并4),铅 物化性质
- 密度：
- 1.574g/cm3
- 沸点：
- 525.6ºC at 760mmHg
- 闪点：
- 268.2ºC
- 折射率：
- 1.887
- 蒸汽压：
- 1.3E-10mmHg at 25°C
盐(8CI,9CI)砷酸(H3酶并4),铅 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LL4385000
- CHEMICAL NAME :
- Fluoranthene, 3,7-dinitro-
- CAS REGISTRY NUMBER :
- 105735-71-5
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C16-H8-N2-O4
- MOLECULAR WEIGHT :
- 292.26
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 mg/kg/10W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 800 ug/kg
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 2500 ug/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 298,255,1993
*** REVIEWS ***
IARC Cancer Review:Animal Limited Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 46,189,1989
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 65,297,1996
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 46,189,1989
IARC Cancer Review:Human Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 65,297,1996
IARC Cancer Review:Group 2B
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 65,297,1996
盐(8CI,9CI)砷酸(H3酶并4),铅 分子结构与计算化学数据
计算化学数据
1.疏水参数计算参考值（XlogP）:4.2
2.氢键供体数量:0
3.氢键受体数量:4
4.可旋转化学键数量:0
5.互变异构体数量:无
6.拓扑分子极性表面积:91.6
7.重原子数量:22
8.表面电荷:0
9.复杂度:486
10.同位素原子数量:0
11.确定原子立构中心数量:0
12.不确定原子立构中心数量:0
13.确定化学键立构中心数量:0
14.不确定化学键立构中心数量:0
15.共价键单元数量:1
