1,5,6,7-四氢-6-甲基嘧啶并[5,4-e]三嗪-5,7-二酮
- 中文名称：
- 1,5,6,7-四氢-6-甲基嘧啶并[5,4-e]三嗪-5,7-二酮
- 中文别名：
-
- 英文名称：
- Pyrimido[5,4-e]-1,2,4-triazine-5,7(6H,8H)-dione,6-methyl-
- 英文别名：
- 6-methyl-8H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione;
Reumycin;
6-Methyl-5.7-dioxo-5.6.7.8-tetrahydro-pyrimido<5.4-e>asymm.triazin;
1-Demethyltoxoflavine;
Reumitsin;
Rheumygin;
1-Demethyltoxoflavin
- CAS No.：
- 5016-18-2
- 分 子 式：
-
C6H5N5O2
- 分 子 量：
- 179.16
- 精确分子量：
- 179.04400
- PSA：
- 93.53000
- InChI：
- The Key: ZLLAXLPOOMLVRF-UHFFFAOYSA-N3
- 危险品标志：
- A poison.
- 安全术语：
- A poison by ingestion, intraperitoneal, and intravenous routes. When heated to decomposition it emits toxic vapors of NOx.
- 分子结构式：
-
- SDS：
- 查看
1,5,6,7-四氢-6-甲基嘧啶并[5,4-e]三嗪-5,7-二酮 物化性质
- 密度：
- 1.544g/cm3
- 折射率：
- 1.605
1,5,6,7-四氢-6-甲基嘧啶并[5,4-e]三嗪-5,7-二酮 安全信息
1,5,6,7-四氢-6-甲基嘧啶并[5,4-e]三嗪-5,7-二酮 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UW7930000
- CHEMICAL NAME :
- Pyrimido(5,4-e)-as-triazine-5,7(1H,6H)-dione,
6-methyl-
- CAS REGISTRY NUMBER :
- 5016-18-2
- LAST UPDATED :
- 199801
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C6-H5-N5-O2
- MOLECULAR WEIGHT :
- 179.16
- WISWESSER LINE NOTATION :
- T66 BVNVN GNN JNJ C1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 41600 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,178,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 42200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,178,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 128 mg/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Blood - changes in spleen
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,178,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 44700 ug/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Blood - changes in spleen
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,178,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 45500 ug/kg
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Blood - changes in spleen
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,178,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >34 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,178,1976
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 750 mg/kg/30D-I
- TOXIC EFFECTS :
- Blood - change in clotting factors
Blood - changes in bone marrow (not otherwise specified)
Blood - changes in platelet count
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 29,516,1984
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 120 mg/kg/60D-I
- TOXIC EFFECTS :
- Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Nutritional and Gross Metabolic - changes in phosphorus
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher
information, see AMBIEH. Volume(issue)/page/year: 21,178,1976
1,5,6,7-四氢-6-甲基嘧啶并[5,4-e]三嗪-5,7-二酮 海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
1,5,6,7-四氢-6-甲基嘧啶并[5,4-e]三嗪-5,7-二酮 下游产品
