甲福明
- 中文名称：
- 甲福明
- 中文别名：
- 二甲双胍;
1,1-二甲基双胍;
甲福明
- 英文名称：
- Imidodicarbonimidicdiamide, N,N-dimethyl-
- 英文别名：
- metformin;
Fluamine;
N,N-dimethylbiguanidine;
Glumetza;
Metiguanide;
Metforminum;
N,N-dimethyl-biguanide;
Dimethylbiguanide;
1,1-Dimethylbiguanide;
N'-dimethylguanylguanidine;
3-(diaminomethylidene)-1,1-dimethylguanidine;
Diabex;
Glucophage;
N,N-dimethylimidodicarbonimidic diamide;
Diabetosan
- CAS No.：
- 657-24-9
- 分 子 式：
-
C4H11N5
- 分 子 量：
- 129.16
- 精确分子量：
- 129.10100
- PSA：
- 88.99000
- EINECS：
- 211-517-8
- InChI：
- InChI=1/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)3
- 危险品标志：
-
- 风险术语：
-
- 安全术语：
-
- 分子结构式：
-
- SDS：
- 查看
甲福明 物化性质
- 密度：
- 1.28 g/cm3
- 沸点：
- 224.1ºC at 760 mmHg
- 闪点：
- 89.3ºC
甲福明 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DU1790000
- CHEMICAL NAME :
- Biguanide, 1,1-dimethyl-
- CAS REGISTRY NUMBER :
- 657-24-9
- LAST UPDATED :
- 199601
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C4-H11-N5
- MOLECULAR WEIGHT :
- 129.20
- WISWESSER LINE NOTATION :
- MUYZMYUM&N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Behavioral - hallucinations, distorted perceptions
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 247 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 146 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Behavioral - hallucinations, distorted perceptions
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 6 gm/kg
- SEX/DURATION :
- female 1-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 2 gm/L/48H
- REFERENCE :
- GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring
St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year:
27,95,1981
*** REVIEWS ***
TOXICOLOGY REVIEW
CLPTAT Clinical Pharmacology and Therapeutics (St. Louis). (C.V. Mosby Co.,
11830 Westline Industrial Dr., St. Louis, MO 63146) V.1- 1960-
Volume(issue)/page/year: 5,480,1964
TOXICOLOGY REVIEW
ADVPA3 Advances in Pharmacology. (New York, NY) V.1-6, 1962-68. For
publisher information, see AVPCAQ. Volume(issue)/page/year: 4,263,1966
推荐供应商
淄博航宇生物科技发展有限公司
甲福明
- 联系人：张经理
- 电 话：15666366704
- 手 机：15666366704
- Cas号：657-24-9
- 包装：100kg
- 纯度：99%
- 价格：洽谈
上海吉至生化科技有限公司
1,1-二甲基双胍
- 联系人：Shirley张
- 电 话：021-57520831
- 手 机：18116052675
- Cas号：657-24-9
- 包装：1gea,250mgea,5gea
- 纯度：95%
- 价格：86.0元 - 662.0元
