甲基二硝基苯,25321-14-6，生产厂家，价格-洛克化工网移动版

返回



基本信息

制备方法及用途

物化性质

安全信息

毒理性

海关数据

甲基二硝基苯

中文名称：: 甲基二硝基苯

中文别名：: 二硝基甲苯;
甲基二硝基苯

英文名称：: Benzene, methyldinitro-

英文别名：: DINITROTOLUENE;
Methyldinitrobenzene;
Toluene,dinitro;
Methlydinitrobenzene;
Dinitrophenylmethane;
ar,ar-dinitro-toluen;
dinitrotoluenes;
dinitro-toluen;
methyldinitro-benzen;
binitrotoluene

CAS No.：: 25321-14-6

分子式：: C₇H₆N₂O₄

分子量：: 182.1

精确分子量：: 182.03300

PSA：: 91.64000

EINECS：: 246-836-1

InChI：: InChI=1/C8H8N2O4/c1-5-3-4-7(9(11)12)8(6(5)2)10(13)14/h3-4H,1-2H33

危险品标志：: 6.1 (Packing group: II) UN NO.

风险术语：: 23/24/25-33

安全术语：: Confirmed carcinogen with experimental tumorigenic and teratogenic data. A poison. Experimental reproductive effects. Mutation data reported. Flammable. When heated to decomposition it emits toxic fumes of NO_x. See also 2,4-DINITROTOLUENE.

分子结构式：

SDS：: 查看

甲基二硝基苯毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XT1300000

CHEMICAL NAME :: Toluene, dinitro-

CAS REGISTRY NUMBER :: 25321-14-6

LAST UPDATED :: 199803

DATA ITEMS CITED :: 34

MOLECULAR FORMULA :: C7-H6-N2-O4

MOLECULAR WEIGHT :: 182.15

WISWESSER LINE NOTATION :: WNR X1 XNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1300 mg/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - respiratory stimulation

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4550 ug/kg/26W-I

TOXIC EFFECTS :: Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12775 mg/kg/Y-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1050 mg/kg

SEX/DURATION :: female 7-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - blood and lymphatic systems (including spleen and marrow) Reproductive - Effects on Newborn - delayed effects

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 196 mg/kg

SEX/DURATION :: female 7-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - behavioral

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2100 mg/kg

SEX/DURATION :: female 7-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1400 mg/kg

SEX/DURATION :: female 7-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - blood and lymphatic systems (including spleen and marrow)

TYPE OF TEST :: Morphological transformation

MUTATION DATA

TEST SYSTEM :: Rodent - rat

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 14,155,1989 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 0.2 mg/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1.5 mg/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,93,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 1.5 mg/m3;Skin JAN 1993 OEL-AUSTRALIA:TWA 1.5 mg/m3;Skin JAN 1993 OEL-BELGIUM:TWA 1.5 mg/m3;Skin JAN 1993 OEL-DENMARK:TWA 1.5 mg/m3;Skin JAN 1993 OEL-FINLAND:TWA 1.5 mg/m3;STEL 3 mg/m3;Skin JAN 1993 OEL-GERMANY;Skin;Carcinogen JAN 1993 OEL-INDIA:TWA 1.5 mg/m3;Skin JAN 1993 OEL-THE NETHERLANDS:TWA 1.5 mg/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 1.5 mg/m3;Skin JAN 1993 OEL-POLAND:TWA 1 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 1.5 mg/m3;Skin;Carcinogen JAN 1993 OEL-TURKEY:TWA 1.5 mg/m3;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 1.5 mg/m3;STEL 5 mg/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO DINITROTOLUENE-air:10H CA TWA 1.5 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992