BLEOMYCIN A6
- 中文名称：
- BLEOMYCIN A6
- 中文别名：
- BLEOMYCIN A6
- 英文名称：
- Bleomycinamide,N1-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-
- 英文别名：
- bleomycin A6;
Zhengguangmycin A6;
Pingyangmycin A6;
N1-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]bleomycinamide
- CAS No.：
- 37293-17-7
- 分 子 式：
-
C60H96N20O21S2
- 分 子 量：
- 0
- 精确分子量：
- 1496.65000
- PSA：
- 733.63000
- 分子结构式：
-
- SDS：
- 查看
BLEOMYCIN A6 物化性质
- 密度：
- 1.53g/cm3
BLEOMYCIN A6 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EC5991325
- CHEMICAL NAME :
- Bleomycinamide, N(sup
1)-(3-((4-((3-aminopropyl)amino)butyl)amino)propyl)-
- CAS REGISTRY NUMBER :
- 37293-17-7
- LAST UPDATED :
- 199607
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C60-H96-N20-O21-S2
- MOLECULAR WEIGHT :
- 1497.88
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 102 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ZKZAEY Zhongguo Kangshengsu Zazhi. Chinese Journal of Antibiotics.
(Zhongguo Kangshengsu Zazhi Bianjibu, 9 Shanbanqiaolu, Chenqdu, 610051 Peop.
Rep. China) V.13- 1988- Volume(issue)/page/year: 15,453,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80330 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ZKZAEY Zhongguo Kangshengsu Zazhi. Chinese Journal of Antibiotics.
(Zhongguo Kangshengsu Zazhi Bianjibu, 9 Shanbanqiaolu, Chenqdu, 610051 Peop.
Rep. China) V.13- 1988- Volume(issue)/page/year: 15,453,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 97780 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ZKZAEY Zhongguo Kangshengsu Zazhi. Chinese Journal of Antibiotics.
(Zhongguo Kangshengsu Zazhi Bianjibu, 9 Shanbanqiaolu, Chenqdu, 610051 Peop.
Rep. China) V.13- 1988- Volume(issue)/page/year: 15,453,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 70530 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ZKZAEY Zhongguo Kangshengsu Zazhi. Chinese Journal of Antibiotics.
(Zhongguo Kangshengsu Zazhi Bianjibu, 9 Shanbanqiaolu, Chenqdu, 610051 Peop.
Rep. China) V.13- 1988- Volume(issue)/page/year: 15,453,1990
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 24500 ug/kg/7W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - death
- REFERENCE :
- ZKZAEY Zhongguo Kangshengsu Zazhi. Chinese Journal of Antibiotics.
(Zhongguo Kangshengsu Zazhi Bianjibu, 9 Shanbanqiaolu, Chenqdu, 610051 Peop.
Rep. China) V.13- 1988- Volume(issue)/page/year: 15,453,1990
