Date Updated: 13/FEB/2006
Version 1.2
Regulation (EC) No 1907/2006
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1 - Product and Company Information
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Product Name L-LOBELINE FREE BASE
Product Number L7149
Company
Century Ba-Shi Building 22A-B,
200020 Shanghai
Technical Phone # 86-21-61415566
Fax 86-21-61415567
E-mail Address
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2 - Hazards Identification
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SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Toxic by inhalation, in contact with skin and if swallowed.
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3 - Composition/Information on Ingredients
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Product Name CAS # EC no Annex I
Index Number
L-LOBELINE FREE BASE 90-69-7 202-012-3 None
Formula C22H27NO2
Molecular Weight 337,5000 AMU
Synonyms 8,10-Diphenyllobelionol *
2-(6-(beta-Hydroxy-phenethyl)-1-methyl-2-piperidy
l)acetophenone *
2-(6-(2-Hydroxy-2-phenylethyl)-1-methyl-2-piperid
inyl)-1-phenylethanone * Inflatine * Lobelin *
(-)-Lobeline * alpha-Lobeline * Lobnico
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4 - First Aid Measures
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AFTER INHALATION
If inhaled, remove to fresh air. If breathing becomes difficult,
call a physician.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
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5 - Fire Fighting Measures
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EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
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6 - Accidental Release Measures
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PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
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7 - Handling and Storage
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8 - Exposure Controls / Personal Protection
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ENGINEERING CONTROLS
Mechanical exhaust.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US)
or CEN (EU). Where risk assessment shows air-purifying respirators
are appropriate use a full-face particle respirator type N99 (US)
or type P2 (EN 143) respirator cartridges as a backup to
engineering controls. If the respirator is the sole means of
protection, use a full-face supplied air respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
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9 - Physical and Chemical Properties
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Appearance Physical State: Solid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
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10 - Stability and Reactivity
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STABILITY
Stable: Stable.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
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11 - Toxicological Information
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RTECS NUMBER: OJ8480000
ACUTE TOXICITY
LD50
Intraperitoneal
Mouse
43500 UG/KG
LD50
Intravenous
Mouse
6300 UG/KG
LD50
Subcutaneous
Rabbit
35 MG/KG
SIGNS AND SYMPTOMS OF EXPOSURE
Stomach pains, vomiting, diarrhea. Exposure can cause:
ROUTE OF EXPOSURE
Multiple Routes: Harmful if swallowed, inhaled, or absorbed
through skin. May cause irritation.
TARGET ORGAN INFORMATION
Central nervous system. Peripheral nervous system.
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12 - Ecological Information
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No data available.
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13 - Disposal Considerations
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SUBSTANCE DISPOSAL
Dissolve or mix the material with a combustible solvent and burn
in a chemical incinerator equipped with an afterburner and
scrubber. Observe all federal, state, and local environmental
regulations.
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14 - Transport Information
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RID/ADR
UN#: 1544
Class: 6.1
PG: III
Proper Shipping Name: Alkaloids, solid, n.o.s.
IMDG
UN#: 1544
Class: 6.1
PG: III
Proper Shipping Name: Alkaloids, solid, n.o.s.
Marine Pollutant: No
Severe Marine Pollutant: No
Technical Name: Required
IATA
UN#: 1544
Class: 6.1
PG: III
Proper Shipping Name: Alkaloids, solid, n.o.s.
Inhalation Packing Group I: No
Technical Name: Required
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15 - Regulatory Information
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CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: T
Toxic.
R-PHRASES: 23/24/25
Toxic by inhalation, in contact with skin and if swallowed.
S-PHRASES: 36/37/39-45
Wear suitable protective clothing, gloves, and eye/face
protection. In case of accident or if you feel unwell, seek
medical advice immediately (show the label where possible).
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
Self-Classification
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16 - Other Information
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WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
unlimitedpaper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
模块 15 - 法规信息
N/A
模块16 - 其他信息
N/A
