去氢倒千里光裂碱
- 中文名称：
- 去氢倒千里光裂碱
- 中文别名：
-
- 英文名称：
- 1H-Pyrrolizine-7-methanol,2,3-dihydro-1-hydroxy-, (1R)-
- 英文别名：
- (1R)-7-(Hydroxymethyl)-2,3-dihydro-1H-pyrrolizin-1-ol;
Dehydroretronecine;
Dehydroretronecin;
Antibiotic DC 52;
DC 52;
dehydroretrorecine
- CAS No.：
- 23107-12-2
- 分 子 式：
-
C8H11NO2
- 分 子 量：
- 153.20
- 精确分子量：
- 153.07900
- PSA：
- 45.39000
- InChI：
- The Key: QFPRRXUPCPFWKD-SSDOTTSWSA-N3
- 安全术语：
- Confirmed carcinogen with experimental carcinogenic and neoplastigenic data. Poison by intraperitoneal route. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
去氢倒千里光裂碱 物化性质
- 密度：
- 1.39g/cm3
- 沸点：
- 361.2ºC at 760mmHg
- 闪点：
- 172.3ºC
- 折射率：
- 1.65
- 蒸汽压：
- 7.54E-06mmHg at 25°C
去氢倒千里光裂碱 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VH7260000
- CHEMICAL NAME :
- Retronecine, 3,8-didehydro-
- CAS REGISTRY NUMBER :
- 23107-12-2
- LAST UPDATED :
- 199510
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C8-H11-N-O2
- MOLECULAR WEIGHT :
- 153.20
- WISWESSER LINE NOTATION :
- T55 AN&TJ D1Q FQ -R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 122 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 56 mg/kg/2W-I
- TOXIC EFFECTS :
- Cardiac - changes in heart weight
Lungs, Thorax, or Respiration - changes in lung weight
Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 350 mg/kg/1Y-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria
Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 120 mg/kg/28W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Skin and Appendages - tumors
Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80 mg/kg/4W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Skin and Appendages - tumors
Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1438 mg/kg/47W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Skin and Appendages - tumors
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - hamster Kidney
- DOSE/DURATION :
- 250 ug/L
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 1,161,1980
*** REVIEWS ***
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 10,333,1976
TOXICOLOGY REVIEW
CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For
publisher information, see JNCIEQ. Volume(issue)/page/year: 60,1171,1976
推荐供应商
湖北恩星生物科技有限公司
去氢倒千里光裂碱
- 联系人：邵经理
- 电 话：16621771607
- 手 机：16621771607
- Cas号：23107-12-2
- 包装：100kg,200kg,300kg,400kg,500kg
- 纯度：
- 价格：64.0元 - 100.0元
