甲氧西林钠
- 中文名称：
- 甲氧西林钠
- 中文别名：
- 甲氧西林钠;
Sodium (2,6-dimethoxyphenyl)penicillin Sodium methicillin
- 英文名称：
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1),(2S,5R,6R)-
- 英文别名：
- methicillin sodium;
(2S,5R,6R)-6-[(2,6-Dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt;
sodium 6-(2,6-dimethoxybenzamido)penicillanate;
Methicillin Sodium;
meticillin sodium;
Sodium (2,6-dimethoxyphenyl)penicillin,Sodium methicillin;
Methicillin sodium salt
- CAS No.：
- 132-92-3
- 分 子 式：
-
C17H20N2O6S.Na
- 分 子 量：
- 402.39733
- 精确分子量：
- 402.08600
- PSA：
- 133.30000
- MDL：
- MFCD07787409
- EINECS：
- 205-083-9
- InChI：
- The Key: MGFZNWDWOKASQZ-UMLIZJHQSA-M3
- 危险品标志：
- 风险术语：
- 36/37/38-42/43
- 安全术语：
- 分子结构式：
-
- SDS：
- 查看
甲氧西林钠 物化性质
- 沸点：
- 640ºC at 760 mmHg
- 闪点：
- 340.9ºC
- 蒸汽压：
- 2.94E-17mmHg at 25°C
甲氧西林钠 安全信息
- 危险类别码：
- 36/37/38-42/43
- 安全说明：
- 26-36
- 安全标志：
- S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
S36:穿戴合适的防护服装。
- 危险标志：
- Xn: Harmful;
甲氧西林钠 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XH8950000
- CHEMICAL NAME :
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid,
6-(2,6-dimethoxybenzamido)-3,3-dimethyl- 7-oxo-,
monosodium salt
- CAS REGISTRY NUMBER :
- 132-92-3
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C17-H19-N2-O6-S.Na
- MOLECULAR WEIGHT :
- 402.43
- WISWESSER LINE NOTATION :
- T45 ANV ESTJ CMVR BO1 FO1& F1 F1 GVO &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human - child
- DOSE/DURATION :
- 600 mg/kg/3D
- TOXIC EFFECTS :
- Liver - other changes
Blood - leukopenia
Blood - eosinophilia
- REFERENCE :
- AJDCAI American Journal of Diseases of Children. (AMA, 535 N. Dearborn St.,
Chicago, IL 60610) V.1-80(3), 1911-50; V.100- 1960-
Volume(issue)/page/year: 135,52,1981
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 17,70,1961
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 17,70,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,826,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AACHAX Antimicrobial Agents and Chemotherapy (1961-70). (Ann Arbor, MI)
1961-70. For publisher information, see AMACCQ. Volume(issue)/page/year:
-,619,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,826,1982
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Cardiac - other changes
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 17,70,1961
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X4186
No. of Facilities: 272 (estimated)
No. of Industries: 1
No. of Occupations: 6
No. of Employees: 11353 (estimated)
No. of Female Employees: 7943 (estimated)
甲氧西林钠 分子结构与计算化学数据
计算化学数据
1.疏水参数计算参考值（XlogP）:无
2.氢键供体数量:1
3.氢键受体数量:7
4.可旋转化学键数量:5
5.互变异构体数量:4
6.拓扑分子极性表面积133
7.重原子数量:27
8.表面电荷:0
9.复杂度:606
10.同位素原子数量:0
11.确定原子立构中心数量:3
12.不确定原子立构中心数量:0
13.确定化学键立构中心数量:0
14.不确定化学键立构中心数量:0
15.共价键单元数量:2
推荐供应商
上海吉至生化科技有限公司
甲氧西林钠
- 联系人：Shirley张
- 电 话：021-57520831
- 手 机：18116052675
- Cas号：132-92-3
- 包装：25mgea,50mgea
- 纯度：98%
- 价格：618.0元 - 1,148.0元
湖北恩星生物科技有限公司
甲氧西林钠
- 联系人：邵经理
- 电 话：16621771607
- 手 机：16621771607
- Cas号：132-92-3
- 包装：100kg,200kg,300kg,400kg,500kg
- 纯度：
- 价格：64.0元 - 100.0元
