甲氨蝶呤钠
- 中文名称：
- 甲氨蝶呤钠
- 中文别名：
- 甲氨蝶呤钠;
N-Chloroacetyl glycyl glycine;
N-Chloroacetylglycylglycine;
Pyridinium, 1-(3-sulfopropyl)-hydroxide, inner salt;
NDSB-201;
3-(1-Pyridino)-1-propanesulfonate;
PYRIDINIUM N-PROPYL SULFOBETAINE;
3-(1-PYRIDINIO)-1-PROPANESULFONATE INNER SALT;
3-(1-PYRIDINIO)PROPANESULFONATE;
3-(1-PYRIDINO)-1-PROPANE SULFONATE;
1-(3-SULFOPROPYL)PYRIDINIUM BETAIN;
1-(3-SULFOPROPYL)PYRIDINIUM BETAINE;
1-(3-SULFOPROPYL)PYRIDINIUM HYDROXIDE;
1-(3-SULFOPROPYL)PYRIDINIUM HYDRO
- 英文名称：
- L-Glutamic acid,N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, sodium salt(1:?)
- 英文别名：
- Methotrexate sodium;
Einecs 239-495-5;
MTX sodium;
METHOTREXATE SODIUM FOR INJECTION
- CAS No.：
- 15475-56-6
- 分 子 式：
-
C20H22N8O5.xNa
- 分 子 量：
- 476.48
- 精确分子量：
- 476.15300
- PSA：
- 213.37000
- EINECS：
- 239-495-5
- InChI：
- InChI=1/C20H22N8O5.2Na/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27);;/q;2*+1/p-2/t13-;;/m0../s13
- 安全术语：
- Poison by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Na2O and NOx. See also METHOTREXATE.
- 分子结构式：
-
- SDS：
- 查看
甲氨蝶呤钠 物化性质
- 外观与性状：
- 橙色至黄色结晶粉末
甲氨蝶呤钠 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MA1240000
- CHEMICAL NAME :
- Glutamic acid,
N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)b
enzoyl)-, sodium salt
- CAS REGISTRY NUMBER :
- 15475-56-6
- LAST UPDATED :
- 199601
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C20-H21-N8-O5.Na
- MOLECULAR WEIGHT :
- 476.48
- WISWESSER LINE NOTATION :
- T66 BN DN GN JNJ CZ EZ H1N1&R DVMYVQ2VO &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 27 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 380 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 90 mg/kg/10D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 200 ug/kg
- SEX/DURATION :
- female 9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 19200 ug/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
before birth)
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Effects on Embryo or Fetus - cytological changes (including
somatic cell genetic material)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 19200 ug/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Specific Developmental Abnormalities - craniofacial
(including nose and tongue)
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 19200 ug/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 1 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
35,1427,1975
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X3245
No. of Facilities: 150 (estimated)
No. of Industries: 1
No. of Occupations: 8
No. of Employees: 3943 (estimated)
No. of Female Employees: 2465 (estimated)
推荐供应商
湖北恩星生物科技有限公司
甲氨蝶呤钠
- 联系人：邵经理
- 电 话：16621771607
- 手 机：16621771607
- Cas号：15475-56-6
- 包装：100kg,200kg,300kg,400kg,500kg
- 纯度：
- 价格：64.0元 - 100.0元
