1-氰基-3,4-环硫丁烷
- 中文名称：
- 1-氰基-3,4-环硫丁烷
- 中文别名：
-
- 英文名称：
- 2-Thiiranepropanenitrile
- 英文别名：
- 3-(thiiran-2-yl)propanenitrile;
Valeronitrile,4,5-epithio;
4,5-Epithiovaleronitrile;
CYANO-3,4-EPITHIOBUTANE;
3-thiiranyl-propionitrile;
Thiiranepropanenitrile;
1-Cyano-3,4-epithiobutan;
1-cyano-3,4-epithiobutane;
4,5-epithiopentanenitrile;
2-Thiiranepropanenitrile
- CAS No.：
- 54096-45-6
- 分 子 式：
-
C5H7NS
- 分 子 量：
- 113.19
- 精确分子量：
- 113.03000
- PSA：
- 49.09000
- InChI：
- The Key: ZAGXORSINWAUSP-UHFFFAOYSA-N3
- 安全术语：
- Poison by subcutaneous route. An experimental teratogen. Experimental reproductive effects.When heated to decomposition it emits toxic fumes of NOx, CN−, and SOx. See also NITRILES.
- 分子结构式：
-
- SDS：
- 查看
1-氰基-3,4-环硫丁烷 物化性质
- 密度：
- 1.129g/cm3
- 沸点：
- 249ºC at 760 mmHg
- 闪点：
- 104.4ºC
- 折射率：
- 1.536
1-氰基-3,4-环硫丁烷 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YV8525000
- CHEMICAL NAME :
- Valeronitrile, 4,5-epithio-
- CAS REGISTRY NUMBER :
- 54096-45-6
- BEILSTEIN REFERENCE NO. :
- 1362236
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C5-H7-N-S
- MOLECULAR WEIGHT :
- 113.19
- WISWESSER LINE NOTATION :
- T3STJ B2CN
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 180 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex)
Behavioral - somnolence (general depressed activity)
Behavioral - muscle weakness
- REFERENCE :
- JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
20037) V.1- 1953- Volume(issue)/page/year: 39,311,1991
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
20037) V.1- 1953- Volume(issue)/page/year: 39,311,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 109 mg/kg
- TOXIC EFFECTS :
- Behavioral - coma
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 18,159,1980
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 375 mg/kg/3D-I
- TOXIC EFFECTS :
- Gastrointestinal - other changes
Kidney, Ureter, Bladder - changes primarily in glomeruli
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year:
26,149,1988
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 540 mg/kg/9D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- REFERENCE :
- JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
20037) V.1- 1953- Volume(issue)/page/year: 39,311,1991
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 36 mg/kg/9D-I
- TOXIC EFFECTS :
- Behavioral - muscle weakness
Nutritional and Gross Metabolic - weight loss or decreased weight gain
Related to Chronic Data - death
- REFERENCE :
- JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
20037) V.1- 1953- Volume(issue)/page/year: 39,311,1991
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 95 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured
before birth)
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 18,159,1980
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 88 mg/kg
- SEX/DURATION :
- female 8-9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 18,159,1980
1-氰基-3,4-环硫丁烷 海关数据
中国海关编码：2926909090
- 概述：
- 2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
