- 中文名称：
-
- 中文别名：
- 1-phenyl-2-(pyrimidin-2-ylamino)ethanol,hydrochloride
- 英文名称：
- Benzenemethanol, a-[(2-pyrimidinylamino)methyl]-,hydrochloride (1:1)
- 英文别名：
- 1-phenyl-2-(pyrimidin-2-ylamino)ethanol,hydrochloride;
Fenyripol hydrochloride;
IN 836;
Fenyripol HCl
- CAS No.：
- 2441-88-5
- 分 子 式：
-
C12H13N3O.ClH
- 分 子 量：
- 251.74
- 精确分子量：
- 251.08300
- PSA：
- 58.04000
- 安全术语：
- Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx and HCl.
- 分子结构式：
-
- SDS：
- 查看
物化性质
- 密度：
- 1.26g/cm3
- 沸点：
- 429.7ºC at 760mmHg
- 闪点：
- 213.7ºC
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DP1230000
- CHEMICAL NAME :
- Benzyl alcohol, alpha-((2-pyrimidinylamino)methyl)-,
monohydrochloride
- CAS REGISTRY NUMBER :
- 2441-88-5
- LAST UPDATED :
- 199503
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C12-H13-N3-O.Cl-H
- MOLECULAR WEIGHT :
- 251.74
- WISWESSER LINE NOTATION :
- T6N CNJ BM1YQR &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 235 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 141,83,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 850 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 141,83,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 360 mg/kg
- TOXIC EFFECTS :
- Behavioral - coma
Cardiac - other changes
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38,
1957-81. Volume(issue)/page/year: 22,87,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Behavioral - coma
Cardiac - other changes
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38,
1957-81. Volume(issue)/page/year: 22,87,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 141,83,1963
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Cardiac - other changes
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38,
1957-81. Volume(issue)/page/year: 22,87,1965
