2,2-二氟-1,3-苯并二噁茂-5-羧酸,656-46-2，生产厂家，价格-洛克化工网移动版

2,2-二氟-1,3-苯并二噁茂-5-羧酸

中文名称：: 2,2-二氟-1,3-苯并二噁茂-5-羧酸

中文别名：: 2,2-二氟-1,3-苯并二噁茂-5-羧酸;
2,2-二氟-1,3-苯并二恶茂-5-甲酸;
2,2-二氟-1,3-苯并二恶茂-5-羧酸

英文名称：: 1,3-Benzodioxole-5-carboxylicacid, 2,2-difluoro-

英文别名：: 2,2-difluoro-1,3-benzodioxole-5-carboxylic acid;
3,4-Difluormethylendioxy-benzoesaeure;
2,2-DICHLOROCYCLOPROPYL PIVALATE;
2,2-Difluorobenzodioxole-5-carboxylic acid

CAS No.：: 656-46-2

分子式：: C₈H₄F₂O₄

分子量：: 202.11

精确分子量：: 202.00800

PSA：: 55.76000

MDL：: MFCD00792417

InChI：: InChI=1/C8H4F2O4/c9-8(10)13-5-2-1-4(7(11)12)3-6(5)14-8/h1-3H,(H,11,12)/p-13

风险术语：: R36/37/38;

安全术语：: S26; S36;

分子结构式：

SDS：: 查看

2,2-二氟-1,3-苯并二噁茂-5-羧酸物化性质

外观与性状：: 淡灰色-黄褐色的粉末带有一种不明的气味
密度：: 1.66 g/cm3
熔点：: 178
沸点：: 266.1ºC at 760 mmHg
闪点：: 114.7ºC
存储条件/存储方法：: 存放在密封容器内，并放在阴凉，干燥处。储存的地方必须远离氧化剂。
稳定性相关：: 远离氧化物。
其它信息：: 1.      性状：液体。
2.      密度（g/mL,25/4℃）：未确定
3.      相对蒸汽密度（g/mL,空气=1）：未确定
4.      熔点（ºC）：178
5.      沸点（ºC,常压）：未确定
6.      沸点（ºC,5.2kPa）：未确定
7.      折射率：未确定
8.      闪点（ºC）：未确定
9.      比旋光度（º）：未确定
10.   自燃点或引燃温度（ºC）：未确定
11.   蒸气压（kPa,25ºC）：未确定
12.   饱和蒸气压（kPa,60ºC）：未确定
13.   燃烧热（KJ/mol）：未确定
14.   临界温度（ºC）：未确定
15.   临界压力（KPa）：未确定
16.   油水（辛醇/水）分配系数的对数值：未确定
17.   爆炸上限（%,V/V）：未确定
18.   爆炸下限（%,V/V）：未确定
19.   溶解性：未确定。

2,2-二氟-1,3-苯并二噁茂-5-羧酸安全信息

海关代码：: 2932999099
危险类别码：: R36/37/38
安全说明：: S26-S36
安全标志：: S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
S36:穿戴合适的防护服装。
危险标志：: Xi

2,2-二氟-1,3-苯并二噁茂-5-羧酸毒理性

生态数据：

对水稍微有危害的，不要让未稀释或者大量产品接触地下水，水道或者污水系统。若无政府许可，勿将材料排入周围环境。

2,2-二氟-1,3-苯并二噁茂-5-羧酸 MSDS

Material Safety Data Sheet

Section 1. Identiﬁcation of the substance
  2,2-Diﬂuoro-1,3-benzodioxole-5-carboxylic acid
    Product Name:
    Synonyms:

Section 2. Hazards identiﬁcation
    Harmful by inhalation, in contact with skin, and if swallowed.
    H315:        Causes skin irritation
    H319:        Causes serious eye irritation
    H335:        May cause respiratory irritation
    P261:        Avoid breathing dust/fume/gas/mist/vapours/spray
    Wear protective gloves/protective clothing/eye protection/face protection
    P280:
    P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
    and easy to do – continue rinsing
    P304+P340:        IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
    P405:        Store locked up

Section 3. Composition/information on ingredients.
    2,2-Diﬂuoro-1,3-benzodioxole-5-carboxylic acid
    Ingredient name:
    CAS number:        656-46-2

Section 4. First aid measures
    Immediately wash skin with copious amounts of water for at least 15 minutes while removing
    Skin contact:
    contaminated clothing and shoes. If irritation persists, seek medical attention.
    Eye contact:        Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
    ﬂushing of the eyes by separating the eyelids with ﬁngers. If irritation persists, seek medical
    attention.
    Inhalation:        Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
    Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.
    Ingestion:

Section 5. Fire ﬁghting measures
    In the event of a ﬁre involving this material, alone or in combination with other materials, use dry
    powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
    should be worn.

Section 6. Accidental release measures
    Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
    standards.
    Respiratory precaution:        Wear approved mask/respirator
    Hand precaution:        Wear suitable gloves/gauntlets
    Skin protection:        Wear suitable protective clothing
    Eye protection:        Wear suitable eye protection
    Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
    for disposal. See section 12.
    Environmental precautions: Do not allow material to enter drains or water courses.

Section 7. Handling and storage
    Handling:        This product should be handled only by, or under the close supervision of, those properly qualiﬁed
    in the handling and use of potentially hazardous chemicals, who should take into account the ﬁre,
    health and chemical hazard data given on this sheet.
    Storage:        Store in closed vessels.

Section 8. Exposure Controls / Personal protection
    Engineering Controls: Use only in a chemical fume hood.
    Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
    General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section 9. Physical and chemical properties
    Not speciﬁed
    Appearance:
    Boiling point:        No data
    Melting point:        No data
    Flash point:        No data
    Density:        No data
    Molecular formula:        C8H4F2O4
    Molecular weight:        202.1

Section 10. Stability and reactivity
    Conditions to avoid: Heat, ﬂames and sparks.
    Materials to avoid: Oxidizing agents.
    Possible hazardous combustion products: Carbon monoxide, hydrogen ﬂuoride.

Section 11. Toxicological information
No data.

Section 12. Ecological information
No data.

Section 13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section 14. Transportation information
Non-harzardous for air and ground transportation.

Section 15. Regulatory information
    No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
    302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
    Title III, Section 313.

SECTION 16 - ADDITIONAL INFORMATION
N/A

2,2-二氟-1,3-苯并二噁茂-5-羧酸海关数据

中国海关编码：2932999099

概述：: 2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素：: 品名, 成分含量, 用途
摘要/Summary：: 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2,2-二氟-1,3-苯并二噁茂-5-羧酸分子结构与计算化学数据

分子结构数据

1、摩尔折射率：39.33

2、

摩尔体积（m³/mol）：121.4

3、

等张比容（90.2K）：328.0

4、

表面张力（dyne/cm）：53.3

5、

极化率（10^-24cm³

）：15.59

计算化学数据

1、疏水参数计算参考值（XlogP）：2.7

2、

氢键供体数量：0

3、

氢键受体数量：6

4、

可旋转化学键数量：0

5、

拓扑分子极性表面积（TPSA）：58.6

6、

重原子数量：14.1

7、

表面电荷：-1

8、

复杂度：250

2,2-二氟-1,3-苯并二噁茂-5-羧酸上游产品

2,2-二氟胡椒酸甲酯 2,2-二氟-1,3-苯并二噁茂 5-溴-2,2-二氟-1,3-苯并二噁唑

2,2-二氟-1,3-苯并二噁茂-5-羧酸下游产品

1-(2,2-二氟苯并[D][1,3]二氧杂环戊烯-5-基)环丙烷甲酸 5-乙酰基-2,2-二氟-1,3-苯并二恶茂 2,2-二氟-1,3-苯并二恶茂-5-甲酰氯; 2,2-二氟-1,3-苯并二噁茂-5-甲酰氯 3-(6-(1-(2,2-二氟苯并[d][1,3]二氧杂环戊烯-5-基)环丙烷甲酰胺基)-3-甲基吡啶-2-基)苯甲酸盐酸盐 1-(2,2-二氟-1,3-苯并二氧戊环-5-基)-N-[1-[(2R)-2,3-二羟基丙基]-6-氟-2-(2-羟基-1,1-二甲基乙基)-1H-吲哚-5-基]-环丙烷甲酰胺