异尼辛
- 中文名称：
- 异尼辛
- 中文别名：
- 异尼辛
- 英文名称：
- 3-Pyridinecarboxamide,N-(2,6-dimethylphenyl)-1,2-dihydro-2-oxo-
- 英文别名：
- isonixin;
Nixyn hermes;
N-(2,6-Dimethylphenyl)-1,2-dihydro-2-oxo-3-pyridinecarboxamide;
Nixyn;
1,2-Dihydro-2-oxo-N-(2,6-xylyl)-3-pyridinecarboxamide;
Isonixine
- CAS No.：
- 57021-61-1
- 分 子 式：
-
C14H14N2O2
- 分 子 量：
- 228.29
- 精确分子量：
- 242.10600
- PSA：
- 61.96000
- EINECS：
- 260-521-6
- InChI：
- The Key: WJDDCFNFNAHLAF-UHFFFAOYSA-N3
- 安全术语：
- Mildly toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
异尼辛 物化性质
- 密度：
- 1.244g/cm3
- 沸点：
- 520.5ºC at 760 mmHg
- 闪点：
- 217.5ºC
- 折射率：
- 1.628
异尼辛 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US4600000
- CHEMICAL NAME :
- 3-Pyridinecarboxamide,
1,2-dihydro-2-oxo-N-(2,6-xylyl)-
- CAS REGISTRY NUMBER :
- 57021-61-1
- LAST UPDATED :
- 199210
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C14-H14-N2-O2
- MOLECULAR WEIGHT :
- 242.30
- WISWESSER LINE NOTATION :
- T6MVJ CVMR B1 F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >6 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,1457,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,1457,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,1457,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,1457,1977
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 281 gm/kg/26W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
Related to Chronic Data - death
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 27,1460,1977
