氯达酮
- 中文名称：
- 氯达酮
- 中文别名：
- 5-chloro-1-[3-(dimethylamino)propyl]-3-phenylbenzimidazol-2-one
- 英文名称：
- 2H-Benzimidazol-2-one,5-chloro-1-[3-(dimethylamino)propyl]-1,3-dihydro-3-phenyl-
- 英文别名：
- 5-chloro-1-[3-(dimethylamino)propyl]-3-phenylbenzimidazol-2-one;
Clodazone;
Clodazone [INN-French];
5-chloro-1-(3-dimethylamino-propyl)-3-phenyl-1,3-dihydro-benzoimidazol-2-one;
Clodazon [INN];
CLODAZON;
2-Benzimidazolinone,5-chloro-1-(3-(dimethylamino)propyl)-3-phenyl;
Clodazona [INN-Spanish];
5-Chloro-1-(3-(dimethylamino)propyl)-3-phenyl-2-benzimidazolinone;
Clodazonum [INN-Latin]
- CAS No.：
- 4755-59-3
- 分 子 式：
-
C18H20ClN3O
- 分 子 量：
- 329.86
- 精确分子量：
- 329.12900
- PSA：
- 30.17000
- InChI：
- The Key: VWXGRWMELBPMCU-UHFFFAOYSA-N3
- 安全术语：
- Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of Cl− and NOx.
- 分子结构式：
-
- SDS：
- 查看
氯达酮 物化性质
- 密度：
- 1.232g/cm3
- 沸点：
- 466.3ºC at 760mmHg
- 闪点：
- 235.8ºC
- 折射率：
- 1.609
氯达酮 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DE1800000
- CHEMICAL NAME :
- 2-Benzimidazolinone,
5-chloro-1-(3-(dimethylamino)propyl)-3-phenyl-
- CAS REGISTRY NUMBER :
- 4755-59-3
- BEILSTEIN REFERENCE NO. :
- 0894387
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C18-H20-Cl-N3-O
- MOLECULAR WEIGHT :
- 329.86
- WISWESSER LINE NOTATION :
- T6MTJ DXQR&R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17,
1968-72. Volume(issue)/page/year: 1,214,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 142 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17,
1968-72. Volume(issue)/page/year: 1,214,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 77 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17,
1968-72. Volume(issue)/page/year: 1,214,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 715 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17,
1968-72. Volume(issue)/page/year: 1,214,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 90 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17,
1968-72. Volume(issue)/page/year: 1,214,1968
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 505 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17,
1968-72. Volume(issue)/page/year: 1,214,1968
